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- Objective To investigate the changes of CD4~+CD28~-T cell and CD4~+CD25~+ regulatory T cell (Treg) subsets in patients with coronary artery disease (CAD). 目的探讨冠心病患者外周血CD4~+CD28~-T细胞和CD4~+CD25~+调节性T细胞(Treg)亚组的变化及意义。
- FTY was additive with regulatory T cells for GVHD inhibition. FTY与调节性T细胞联合抑制了GVHD。
- Summary: The potency of regulatory T cells is impressie, but unexplained. 总结:调节性T淋巴细胞的效能值得注重,但尚无法解释。
- Aire gene does not affect the production of CD4~+CD25~+ regulatory T cells. 结果表明Aire基因不影响CD4+CD25+调节性T细胞的产生。
- Objective:To clarify the role of Aire on the production of regulatory T cells on mice. 目的:探讨自身免疫调节因子(Aire)基因是否影响调节性T细胞的产生。
- Objective:To evaluate the effect of leflunomide(LEF)on CD4+CD25+ regulatory T cells(Treg). 目的:评价新型免疫抑制剂来氟米特应用对CD4+CD25+调节性T淋巴细胞的影响。
- These regulatory T cells can't keep the system in line, and it starts attacking things it shouldn't? 这些调节性T细胞不能保证系统正常工作,并且它开始攻击它不该攻击的东西?
- Failure of the regulatory T cells to control the frontline fighters leads to autoimmune disease. 调节T细胞障碍不能控制第一线活力导致自身免疫疾病。
- The inducible costimulator (ICOS) and its ligand GL50 are a couple of the newest member of the CD28/B7 family involved in regulating T cell activation. ICOS及其配体GL50是最近发现的CD28/B7家族的一对新成员。
- Alexander Marson: Yes.In mice, if you remoe all the regulatory T cells, what you see is a massie, multiorgan autoimmune disease. 是的,在小鼠中,如果你去除所有的调节性T细胞,你将看到的是多器官性、严重的自身免疫性疾病。
- GLSPs also increased CTL and TH cells in the peripheral blood lymphocyte of S180 tumorbearing mice with no effect on regulatory T cells. 此外灵芝孢子多糖对S180肉瘤荷瘤小鼠外周血杀伤性T淋巴细胞亚群和辅助性T淋巴细胞亚群有一定的增强作用,但对调节性T淋巴细胞亚群并无明显作用。
- They are the main component of thymic microenvironment, and play important role on T lymphocyte differentiation and regulation T cell function. 这些可溶性物质是构成胸腺微环境的主要因素,在T细胞分化和发育成熟过程中起重要的调节作用。
- Regulatory T cells can be found in tolerated grafts and contribute to the acquisition of a state of priilege in those tissues. 在产生免疫耐受的移植物中可发现调节性T淋巴细胞,并对移植组织具有保护性作用。
- In addition, these regulatory T cells are unable to cure mouse models of an inflammatory disease that closely resembles human IBD. 此外,这些调节性t细胞不能治愈小鼠模型的发炎性疾病,这种疾病极为相似人类传染性法氏囊病。
- Alexander Marson: Yes.In mice, if you remove all the regulatory T cells, what you see is a massive, multiorgan autoimmune disease. 是的,在小鼠中,如果你去除所有的调节性T细胞,你将看到的是多器官性、严重的自身免疫性疾病。
- Unlike other T cells, which kill infected cells or secrete inflammatory molecules known as cytokines, regulatory T cells dampen immune responses. 调节性T细胞不像其他种类的T细胞,它不会杀死感染细胞或分泌发炎性分子(细胞素),反而会减缓免疫反应。
- In the presence of allergen or anti-CD3 mAb and anti-CD28 mAb, we studied the function of CD4+ CD25+ regulatory T cells isolated from non-allergy donors and allergy donors. 分别用变应原或联合应用抗CD3单抗和抗CD28单抗,刺激来源于正常对照组和患者的CD4~+CD25~+调节性T细胞和CD4~+CD25~-T细胞,ELISA、3H-TdR等检测CD4~+CD25~+调节性T细胞功能。
- CD4+CD25+ regulatory T cell is a special kind of regulatory T cells,which participates in autoimmune regulation and maintains immunological tolerance. CD4+CD25+调节性T细胞是一种特殊的调节性T细胞,参与自身免疫调节,维持自身免疫耐受。
- Abstract:Allograft transplant outcome, rejection or tolerance, depends upon striking a balance between the pertinent cytopathic and regulatory T cells. 摘要:异体移植的结果,排斥或耐受性,取决于之间求取平衡有关的细胞和调节性t细胞。
- CD+4CD+25 regulatory T cells is an important subpopulation,which can actively mediate immunological tolerance to autoantigen in organism and inhibit anti-tumor immunological response although its mechenism of immunosupression in vivo is not clear. CD4+CD2+5调节性T细胞是调节性T细胞的一个重要亚群,它能够以主动性的方式介导机体对自身抗原的免疫耐受以及抑制抗肿瘤免疫应答,但在体内其具体的免疫抑制机制目前还不清楚。