In the presence of allergen or anti-CD3 mAb and anti-CD28 mAb, we studied the function of CD4+ CD25+ regulatory T cells isolated from non-allergy donors and allergy donors.

• 分别用变应原或联合应用抗CD3单抗和抗CD28单抗，刺激来源于正常对照组和患者的CD4~+CD25~+调节性T细胞和CD4~+CD25~-T细胞，ELISA、3H-TdR等检测CD4~+CD25~+调节性T细胞功能。