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- Aim The phage display antibody library was constructed to obtain functional anti Fas Fab. 目的构建噬菌体抗体库,获得具有功能的抗Fas?Fab噬菌体抗体。
- The phage display antibody library is developed by reasonably combining the antibody library technology and phage surface display system. 将抗体库技术与噬菌体表面展示系统有机地结合就发展成为噬菌体展示抗体库。
- Advance in Phage Display Antibody Library 噬菌体抗体库研究进展
- Objective To select anti VEGF (vascular endothelial growth factor) antibodies (Fab fragments) from human phage display antibody library and to identify their specification and activities. 目的 从人噬菌体Fab抗体库中筛选抗人血管内皮细胞生长因子 (VEGF)抗体克隆 ,并对其特异性及活性进行分析 ,为后续工作奠定基础。
- Keywords Pemphigus vulgaris Phage display antibody technique Antibody library; 天疱疮;寻常;噬菌展示体抗技术;抗体文库;
- Generation and Characterization of a Single-chain Antibody Fragment against White Spot Syndrome Virus of Shrimp from Phage Display Antibody Library 从噬菌体展示抗体文库筛选对虾白斑综合征病毒的单链抗体
- Keywords hepatocyte growth factor/scatter factor;phage display antibody library;affinity maturation;internalizing antibody; 肝细胞生长因子受体;噬菌体抗体库;亲和力成熟;内化抗体;
- phage display antibody library. 噬菌体抗体库
- phage display antibody library 噬菌体抗体库
- Construction of Human Na(?)ve Phage Display Antibody Library and Primary Screening of the Fab Antibodies Against gp96 人天然Fab段噬菌体抗体库的构建及抗gp96抗体的初步筛选
- In the present paper the application of DNA library, phage display random peptide library, phage antibody library, etc. in the research of serodiagnostic reagents and their special values were reviewed. 本文综述了基因文库、噬菌体展示肽库及噬菌体抗体库技术在血清学诊断试剂研制中的应用及其各自的优点。
- Methods Construct and pan human Fab antibody library to influenza virus Sydney strain (H3N2) from vaccinated donors by using phage display technology and secreted expression in \%E. 用纯化的流感病毒A Sydeny 5 97(H3N2 )为固相抗原筛选抗体Fab段 ,并在大肠埃希菌中进行分泌性表达。
- Phage display antibody repertoire library technique 噬菌体表面全套抗体库技术
- Keywords receptor tyrosine kinase;phage display;antibody library;biopanning; 酪氨酸激酶受体;噬菌体呈现;抗体库;生物筛选;
- Keywords prostate carcinoma;phage display technology;prostate specific membrane antigen;biopanning;phage antibody library; 前列腺癌;噬菌体展示技术;前列腺特异性膜抗原;亲和筛选;噬菌体抗体库;
- Methods mRNA was extracted from lymphocytes of a volunteer with high level antibody to HBsAg. Fab phage display library was constructed. 方法 采用噬菌体抗体库技术 ,从乙肝疫苗免疫后健康人外周血淋巴细胞中提取抗体基因建立抗体库 ,用纯化的HBsAg筛选Fab抗体 ;
- Utilizing the technology of phage surface display, special antibody can be gained from the human naive Fab phage display library, which can be used as a new therapy for tumors. 本研究构建的人天然Fab段噬菌体抗体库可为进一步筛选特异性抗体,用于免疫治疗打下基础。
- By using combinatorial library and phage display technologies on a hapten-specific antibody we were able to demonstrate that a peripheral carrier imprint indeed exists. 利用组合库和噬菌体展示技术,我们证明半抗原特异性抗体确实存在有外围载体的某些遗迹。
- Keywords Natural antoantibody;Keratin;Anti-keratin autoantiobdy;Phage display antibody repertoire;phage antibody; 天然自身抗体;角蛋白;抗角蛋白自身抗体;噬菌体呈现抗体库;噬菌体抗体;
- This article is using phage display technology constuncted a naive library of phage-display human Fab library. Obtained the completely humanized Fab antibody against idiotypic antibody of schistosoma japonicum from large naive phage-display library. 本文应用噬菌体抗体库技术,构建大容量天然人源Fab抗体库,从中富集、筛选全人源日本血吸虫抗独特型抗体并进行初步鉴定,为研制可用于人体血吸虫病免疫预防的抗独特型抗体疫苗奠定基础。