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- AIM: To construct a yeast two-hybrid cDNA library of hydroxycamptothecin-resistant human colon cancer cell line SW1116/HCPT in yeast cells. 目的:构建羟基喜树碱耐药结肠癌细胞株SW1116/HCPT细胞的酵母双杂交cDNA文库.
- CLT can induce apoptosis in vitro in human colon cancer cell line CCL 229.The apoptosis inducing effect may be G1 phase specific. 克霉唑对人结肠癌细胞系CCL229有明显的凋亡诱导作用,并且能特异地诱导G1期细胞凋亡。
- Objective The study investigated the effect of gastrin on tyrosine phosphorylation and protein expression of focal adhesion kinase (FAK) in human colon cancer cells. 目的研究胃泌素对人结肠癌细胞信号分子黏着斑激酶(FAK)酪氨酸磷酸化和蛋白质表达的影响。
- MPA has significant inhibitory effect on the growth of human colon cancer cells,which may be related to Fas expression upregulation on cancer cell surface and G_(1) phase arrest. MPA对结肠癌细胞具有显著的抑制作用和诱导凋亡的作用,其机制可能与MPA使结肠癌细胞停滞于G1期及细胞表面Fas表达上调有关。
- Gastrin-gastrin receptor signal transduction pathway can obviously induce u-PA expression in human colon cancer cells via activating the phosphorylation of p38 kinase. 胃泌素与其受体结合后,可通过p38 MAPK信号转导通路诱导结肠癌细胞表达u-PA。
- Objective To investigate the effects of deoxycholic acid(DCA) on the proliferation of HT-29 human colon cancer cells and the effects of berberine on activator protein-l(AP-l), cyclooxygenase-2(COX-2) expression of HT-29 cells induced by DCA. 目的 研究脱氧胆酸(DCA)对HT-29人结肠癌细胞增殖的作用及黄连素(BER)对DCA诱导下HT-29细胞激活蛋白-1(AP-1)、环氧合酶-2(COX-2)表达的影响。
- Objective To study the effect of gastrin on the mRNA and protein expression of urokinase-type plasminogen activator (u-PA) in human colon cancer cells and detect the role of p38 MAPK in this process. 目的研究胃泌素对人结肠癌细胞尿激酶型纤溶酶原激活物(u-PA)mRNA和蛋白表达的影响,探讨信号分子p38 MAPK在其中的作用。
- METHODS: Human colon cancer cell line DLD1-TRAIL/R cells that were resistant to TRAIL-expressing adenovector(Ad/gTRAIL) were treated with Ad/gTRAIL combined with different chemotherapeutic agents. 方法:将不同化疗药物联合重组腺病毒载体(Ad)介导的TRAIL基因处理对Ad/gTRAIL耐药的结肠癌DLD1-TRAIL/R细胞,通过MTT法检测治疗后肿瘤细胞的存活率,以评价化疗药物对TRAIL基因耐药的逆转作用;
- The expression of c-myc was not significant different in SW116 and Colo-320 cells treated by 5-aza-dC. Conclusion The expression of p16 INK4A and APC genes was regulated by DNA methylation in three human colon cancer cells. 结论 三株人结肠癌细胞中 ,5 aza dC均可诱导 p16 INK4A和APC的表达 ,但对 p2 1WAF1和c myc无明显影响。
- Mandy M.Y. Tin, Chi-Hin Cho, Kelvin Chan, et al. Astragalus saponins induce growth inhibition and apoptosis in human colon cancer cells and tumor xenograft[J]. Carcinogenesis, 2007, 28(6): 1347. 章志翔;戚峰;周德俊;等.;氟尿嘧啶联合黄芪对小鼠胃癌组织氨基酸代谢的影响[J]
- METHODS: Human breast cancer cell line MCF 7, human gastric cancer cell line BGC 823, human prostate cancer cell line DU 145, and human colon cancer cell line HT 29 were treated with 5 Aza CdR. 方法:用5-Aza-CdR作用人乳腺癌细胞系MCF-7、人胃癌细胞系BGC-823、人的前列腺癌细胞系DU-145和人结肠癌细胞系HT-29。
- Oxaliplatin can significantly inhibit the proliferation and induces G2/M arrest in human colon cancer cell line SW480.The mechanism is related to up-regulated expression of caspase-8. 奥沙利铂能够明显抑制人结肠癌细胞株SW480的增殖,诱导SW480细胞发生G2/M期阻滞,其作用机制可能与caspase-8表达上调有关。
- Apoptosis study of human colon cancer cells induced by ceramide 神经酰胺诱导人结肠癌细胞凋亡作用
- Functional expression of Fas ligand in human colon cancer cells 大肠癌细胞表达的Fas配体具有功能性
- EXPRESSION OF Fas LIGAND IN HUMAN COLON CANCER CELL LINES Fas配体在大肠癌细胞中的表达
- Potassium Antimonyl Tartrate Induces Apoptosis of Human Colon Cancer Cells 酒石酸锑钾诱导人结肠癌细胞凋亡
- Up-regulation of Fas expression by 5-fluorouracil in human colon cancer cells 5-氟尿嘧啶对大肠癌Fas蛋白表达的调控作用
- Establishment of Drug-resistant Line HCT_(V2000) of Human Colon Cancer Cells 人结肠癌耐药细胞系HCT_(V2000)的建立
- Expression and Modulation of Functional Fas ligand in Human Colon Cancer Cells 功能性Fas配体在大肠癌细胞的表达及其调控
- Cytokines upregulate Fas ligand protein expression in human colon cancer cells 细胞因子上调大肠癌细胞Fas配体表达
