Oxaliplatin can significantly inhibit the proliferation and induces G2/M arrest in human colon cancer cell line SW480.The mechanism is related to up-regulated expression of caspase-8.

• 奥沙利铂能够明显抑制人结肠癌细胞株SW480的增殖,诱导SW480细胞发生G2/M期阻滞,其作用机制可能与caspase-8表达上调有关。