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- Genes involved in transcription, RNA processing, and cell cycle regulation were particularly affected. 这些受影响的基因主要基因涉及转录、RNA加工细胞周期调控等过程。
- The isoform CDK11p58 is specifically translated in G2/M phase and has much relation with cell cycle regulation. CDK11p58特异地在G2/M 期表达，和细胞周期的调节有着密切的联系。
- The transcription factor,E2F,playing a critical role in cell cycle regulation,is involved in the pathophysiological process of restenosis. 2F是调控细胞周期进程一个关键的转录因子,而且在血管再狭窄的病理过程中也起着非常重要的作用。
- Data from this study indicate that the inhibition of p15INK4B and p21WAF1/cip1 may be one of the mechanisms by which HDAC3 participates in cell cycle regulation and oncogenesis. 干涉质粒能诱导p15INK4B基因表达活性的升高，而对p21WAF1/cip1的表达没有什么影响。本研究表明去乙酰化酶3可能是通过抑制p15INK4B和p21WAF1/cip1这种方式来参与周期调控和癌症发生的。
- Research indicated that PI3K and MAPK signal pathways were associated with biological behaviors such as cell migration, inflammation, cell proliferation and cell cycle regulation. 已有的研究表明PI3K和MAPK信号传导通路参与了细胞迁移、炎症反应、细胞增殖和细胞周期调控等一系列过程,在肾组织纤维化的发生发展中发挥重要作用。
- Objective To analyze the correlation of cell cycle regulation factors Cyclin D1, CDK. 4, P1 6 protein and p16 gene expression with clinicopathologic features and the prognosis in colorectal carcinoma. 目的 探讨细胞周期调控因子Cyclin D1、CDK4、P16蛋白及p16基因表达与大肠癌的临床病理特征及预后的关系。
- In fact, as a specific molecular chaperone, HSP90 proteins are possibly involved in many important physiological processes such as signal transduction, cell cycle regulation and hormone response. 事实证明，作为一种特异的分子伴侣，HSP90除在细胞正常生长和应急保护中具有重要生理功能外，还与信号传导、细胞周期调控、激素应答等细胞内重要生理过程有关。
- In order to build up a gastric carcinoma cell expressing human cyclin G2 gene stably, a useful tool for the research on the function of cyclin G2 in gastric carcinoma cell cycle regulation was made. 应用脂质体基因转染技术建立稳定表达cyclin G2基因的胃癌克隆细胞，为深入研究cyclin G2在胃癌细胞周期调控的作用和机制提供理想的生物学模型。
- In summary, we here report that cyclin D3/CDK11p58 signaling is involved in the transcriptional regulation in eukaryotic cells as well as the cell cycle regulation. 综上所述，我们发现cyclin D3/CDK11p58信号途径除能调控细胞周期外，也参与了真核细胞的转录调控。
- Objective To clarify the role of a cell cycle regulator, cyclin D1 and CDK6 in patients with gastric carcinoma. 目的检测细胞周期蛋白D1(cyclin D1)和细胞周期蛋白质依赖激酶6(CDK6)在胃癌组织中的表达情况,分析其表达与胃癌的临床病理因素和预后之间的关系。
- Many researches show that Skp2 can interact with many cell cycle regulating factors including p27, and lead to their ubiquitination and degeneration. Skp2是F-box蛋白家族的一员。研究发现，Skp2可与包括p27在内的多种细胞周期调控因子相互作用，导致它们的泛素化降解。
- Micro Mechanisms of Cell Cycle Regulation and Checkpoint Control 细胞周期调控的分子机制与关卡调控
- cell cycle; cell cycle regulatory proteins;glomerular disease;P27 细胞周期；细胞周期调控蛋白；肾小球疾病；P27
- The Effect of Dougenguanshitong Oral Liquids on the Cell Cycle Regulation Factor of Modeled Esophageal Carcinoma Rats 豆根管食通口服液对食管癌造模大鼠细胞周期调控因子的影响
- Flow Cytometry applyed to analysis cell cycle. 采用流式细胞仪分析细胞周期。
- And cell cycle was arrested of G0/ G1 phase. 并且将细胞周期阻滞于G0/G1期。
- Effects of Combination with Benazepril and Valsartan on Renal Cell Cycle Regulation in Nephrotic Rats 苯那普利和缬沙坦联合应用对肾病大鼠肾脏细胞周期调控的影响
- The Effects of Ruangan Granule (RGG) on p~(21) Expression and Cell Cycle Regulation Experimental Cirrhosis in SD Rats 软肝冲剂对肝硬化大鼠p~(21)及细胞周期调控的影响
- E1A gene can effectively enhance the radiosensitivity of human cervical carcinoma cells and its mechanisms of action may relate to the suppression of Her-2 expression and a redistribution of cell cycles regulated by E1A gene. E1A基因能够明显提高人宫颈癌细胞对放射线的敏感性,其作用机制可能与E1A基因抑制了该细胞Her-2基因的表达,使细胞周期再分布有关。
- Difference expression of gene for laryngeal squamous cell carcinoma by cDNA microarray and signal pathways of cell cycle regulation and cell apoptosis cDNA微阵列结合信号通路分析喉鳞癌差异表达基因
