E1A gene can effectively enhance the radiosensitivity of human cervical carcinoma cells and its mechanisms of action may relate to the suppression of Her-2 expression and a redistribution of cell cycles regulated by E1A gene.

• E1A基因能够明显提高人宫颈癌细胞对放射线的敏感性,其作用机制可能与E1A基因抑制了该细胞Her-2基因的表达,使细胞周期再分布有关。