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- The clinical value of asialoglycoprotein receptor imaging for determining liver functional reserve. 非唾液酸糖蛋白受体显像在评估肝储备功能方面的应用价值。
- Galactosyl recognizes asialoglycoprotein receptor(ASGP-R) on liver cell surface specifically, and was widely used as ligands in designing liver-target drug delivery systems. 半乳糖基可以特异性识别肝细胞表面的去唾液酸糖蛋白受体,而壳聚糖作为一种生物相容性优良的天然高分子材料已广泛地应用于生物材料领域。
- Neoglycoalbumin(NGA), the special ligand of asialoglycoprotein receptor on the hepatocyte is linked via a butanediamide bridge to the free amino group of primaquine(PQ) to form a conjugator NGA PQ. 以肝细胞膜无唾液酸糖蛋白受体的特异性配体半乳糖新糖白蛋白(NGA)作载体,通过丁二酰胺桥将其与抗疟药磷酸伯氨喹(PQ)偶联,制备了一种肝靶向抗疟药NGA-PQ。
- Objective To reduce extrahepatic side effects of ACV in treatment of chronic hepatitis B , the drug was conjugated with lactosaminated poly L lysine (Lac PLL) which selectively enters hepatocyte by Asialoglycoprotein receptor. 目的 减少抗病毒药阿昔洛韦 (Acyclovir ,ACV)在治疗乙型肝炎中的肝外毒副作用 ,获得肝靶向ACV偶联物。
- asialoglycoprotein receptor developer 去唾液酸糖蛋白受体显像剂
- asialoglycoprotein receptor(ASGPR) 涎酸糖蛋白受体
- Asialoglycoprotein receptor, transferrin receptor and receptors for lactoferrin, insulin, epidermal growth factor, folic acid and mannose have been used in receptor-mediated gene delivery. 受体介导的基因转移有安全、低免疫原性、相对靶向性、载体制备简单、易规模化等许多优点。
- Keywords marmota;asialoglycoprotein receptor;gene therapy; 旱獭;去唾液酸糖蛋白受体;基因治疗;
- Keywords Asialoglycoprotein receptor;Marmota himalayan;Polyclonal antibody;Targeting therapy; 去唾液酸糖蛋白受体;中国旱獭;多克隆抗体;靶向治疗;
- Keywords asialoglycoprotein receptor(ASGP-R);tumor necrosis factor(TNF);hepatic carcinoma; 关键词无唾液酸糖蛋白受体(ASGP-R);肿瘤坏死因子(TNF);肝癌;
- Keywords Single-chain Fv antibody;Enzyme linked immunosorbent assay;Asialoglycoprotein receptor;Fusion protein; 单链抗体;酶联免疫吸附测定;去唾液酸糖蛋白受体;融合蛋白;
- Keywords Asialoglycoprotein receptor;Chinese marmota;liver diseases;gene therapy;Polyclonal antibody; 关键词中国旱獭;去唾液酸糖蛋白受体;多克隆抗体;肝脏疾病;基因治疗;
- Keywords N-Lactosyl chitosan;Methotrexate;Asialoglycoprotein receptor;Liver-targeting;Polymeric prodrug; 乳糖酰基壳聚糖;甲氨喋呤;去唾液酸糖蛋白受体;肝靶向;高分子前体药;
- Optimized expression of a single-chain Fv antibody against human asialoglycoprotein receptor and determination of its affinity constant 去唾液酸糖蛋白受体特异性单链抗体的优化表达及亲和常数的测定
- A sensory receptor that detects warmth. 热探测器测量热量的敏感接受器
- Establishment of enzyme linked immunosorbent assay of autoantibodies to asialoglycoprotein receptor and its clinical application 抗去唾液酸糖蛋白受体酶联免疫检测法的建立及临床初评
- Cloning, prokaryotic expression and polyclonal antibody preparation of the asialoglycoprotein receptor of marmota himalayan 中国旱獭去唾液酸糖蛋白受体糖基结合域的原核表达与多克隆抗体的制备
- Keywords Asialoglycoprotein receptor;Liver target;cholesteryl galactosides;Bifunctional reagent;Branched reagent;Synthesis; 无唾液酸糖蛋白受体;肝靶向;胆甾半乳糖苷;双功能试剂;分支试剂;合成;
- The liver not only is the receptor of dietary fat. 肝脏是日粮脂肪的接受者。
- A sensory receptor detects warmth. 热探测器是测量热量的敏感接受器。