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- To investigate the relationship between gene polymorphism of aldosterone synthase (CYP11B2) and essential hypertension EH.Methods 1. 本研究旨在观察我国华南地区汉族人群醛固酮合成酶(CYP11B2)基因344C/T多态性与高血压病(EH)相关性。
- Objective To evaluate the influence of gene polymorphism of aldosterone synthase gene CYP11B2(-344T/C) on RAAS in Han Nationality essential hypertensive patients in Beijing. 摘要目的探讨醛固酮合成酶基因CYP11B2(-344T/C)多态性对北京汉族高血压患者肾素-血管紧张素-醛固酮(RAAS)系统的影响。
- Methods Polymerase chain reaction was used to detect the polymorphism of aldosterone synthase gene CYP11B2(-344T/C) in 345 hypertensive patients (EH) and 156 normotensive controls (NE). 方法采用多聚酶链式反应结合限制性内切酶片段长度多态性分析方法，检测345例原发性高血压(EH)病人和156例健康人(NE)醛固酮合成酶基因CYP11B2(-344T/C)多态性。
- Methods:Gradient PCR was employed in analysis of aldosterone synthase(CYP11B2)gene polymorphisms,and gel Imaging Technology was used to determine the optimal annealing temperature. 方法:采用梯度PCR对醛固酮合酶基因(CYP11B2)进行扩增,通过凝胶呈像技术判断CYP11B2基因最佳退火温度。
- aldosterone synthase (CYP11B2) gene 醛固酮合成酶（CYP11B2）基因
- aldosterone synthase gene CYP11B2 醛固酮合成酶基因
- Association between aldosterone synthase gene polymorphism and hypertrophic cardiomyopathy 醛固酮合成酶基因多态性与肥厚型心肌病相关性研究
- Association between aldosterone synthase gene polymorphism and primary hypertension in Chinese Han population 武汉地区汉族人群醛固酮合酶基因多态性与原发性高血压的关系
- Keywords Hypertension;Gene;Left ventricular hypertrophy;Aldosterone synthase gene; 关键词高血压;基因;左心室肥厚;醛固酮合成酶;
- Keywords aldosterone synthase gene;polymorphism;hypertension;hypertrophy;left ventricular; 醛固酮合成酶基因;多态性;高血压;肥大;左心室;
- The relationship of aldosterone synthase gene polymorphism, blood pressure, glucose and blood lipid and susceptibility to acute cerebral infarction 醛固酮合成酶基因多态性和血压、血糖、血脂相互作用与急性脑梗死的易感性
- The relationship of aldosterone synthase gene polymorphism, dietary habits and susceptibility to acute cerebral infarction 醛固酮合成酶基因多态性及生活习惯与急性脑梗死易感性的关系
- Keywords Gene polymorphism;Hypertention;Prodromal symptoms of apoplexy;Angiotensin converting enzyme （ACE）;Aldosterone synthase; 基因多态性;高血压;中风先兆证;血管紧张素转换酶;醛固酮合成酶;
- Keywords Essential hypertension;Kazakh ethnic;endothelial nitric oxide synthase （eNOS） gene;aldosterone synthase gene;gene polymorphism;synergistic effect of gene; 原发性高血压;哈萨克族;醛固酮合成酶基因;内皮型一氧化氮合酶基因;基因多态性;基因协同作用;
- Synthase polymorphism has become a focus of study. 合酶基因多态性已成为研究的热点。
- Eplerenone is a selective aldosterone antagonist. 依普利酮是选择性的醛甾酮拮抗药。
- aldosterone synthase gene 醛固酮合成酶基因
- aldosterone synthase 醛固酮合酶
- Aldosterone synthase CYP11 B2 醛固酮合成酶基因CYP11B2
- Aldosterone is the most important and powerful salt cortex hormone. 醛固酮是人体内最重要、作用最强的盐皮质激素。
