Methods Polymerase chain reaction was used to detect the polymorphism of aldosterone synthase gene CYP11B2(-344T/C) in 345 hypertensive patients (EH) and 156 normotensive controls (NE).

• 方法采用多聚酶链式反应结合限制性内切酶片段长度多态性分析方法，检测345例原发性高血压(EH)病人和156例健康人(NE)醛固酮合成酶基因CYP11B2(-344T/C)多态性。