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Keywords Syringopicroside;pharmacokinetics;HPLC;Protein binding fraction; 丁香苦苷;药动学;高效液相;血浆蛋白结合率;
Thyroperoxidase (TPO)is a glycosylated protein bound to the apical plasma membrane of thyrocytes.It is the key enzyme in the synthesis of thyroid hormones. TPO甲状腺过氧化物酶是甲状腺细胞膜上的一种糖蛋白,是合成甲状腺激素的关键酶。
It is a water-insoluble, highly protein bound, lipophilic compound that has unique pharmacokinetic characteristics that render it ideal for use with ambulatory surgery. 非水溶性，高蛋白，高脂混合物具有的药代动力学特征使它适用于门诊手术。
Compared with gully bottom, plateau, terrace and sloping lands led to higher Mn in carbonate and organic matter bound fractions but lower Mn in oxide bound fraction. 交换态锰在塬面、梯田土壤含量较低，在坡地和沟道土氧化物结合态锰的含量显著低于沟道土壤；
Results: The serum NPSH decreases markedly in children with diarrhea and pneumonia, the total sulfhydryl and protein bind sulfhydryl do not change obviously. 结果：表明肺炎及腹泻患儿血清NPSH明显降低，总巯基和蛋白结合巯基无明显改变。
The protein binding selectivity of clozapine was discussed. 讨论了氯氮平蛋白结合作用的选择性。
And purified soluble linoleate isomerase was gained by refolding of denatured LI protein bound to Ni2+-NTA, and the purified recombinant linoleate isomerase possessed biological activity(5.12 U/mg),which was 2.5 times of natural linoleate isomerase. 采用Ni2+-NTA柱上复性法获得有活性的纯化重组亚油酸异构酶;其比活力5.;12U/mg;是天然亚油酸异构酶比活力的2
For example, when the scientists added the protein to short pieces of DNA containing the six nucleotides that make up a human telomeric repeat, the human POT1 protein bound poorly. 而人类POT蛋白为二聚体，因此需要更长的端粒DNA才能嵌入二聚体内部的沟陷中发生有效结合。
OBJECTIVE To study the plasma protein binding rate of harmine hydrochloride. 目的:测定盐酸去氢骆驼蓬碱的血浆蛋白结合率。
After renaturation, AIF protein binded DNA and induced nuclear apoptosis. 经EMSA与Hoechst 33258染色实验证实:获得的AIF蛋白具有良好地与DNA结合并可诱导肿瘤细胞核凋亡的能力,凋亡率为37%25。
Plasma protein binding: Drugs are tra orted in the bloodstream partly in solution as free （u ound） drug and partly bound to blood components （eg, plasma protei , blood cells）. 血浆蛋白结合药物在血流中转运时，一部分是以游离药溶解于血液中（非结合型），另一部分则与血液成分（如血浆蛋白、血细胞）相结合。
DNA helix can have subtle structural variations in its grooves and its physical arrangement that affect how well proteins bind to it. 在其凹槽和物理排列方面，DNA螺旋可以有微妙的结构变化，从而可以影响蛋白与之结合的程度。
Circularization could provide for translational regulation.Regulatory proteins bound to either the 5’or 3’untranslated regions could disrupt or enhance circularization. 环化为调控蛋白质翻译提供了一种手段，调节蛋白结合在5’端与3’端的非翻译区，促进或破坏环化。
This variation of binding fractions indicates that the adding of EDTA was helpful for the release of heavy metals into pore water or to form the easily releasing binding fraction. 此转移现象非常有利于芥菜对土壤中铅、铜及镉之萃取吸收。
Mundy J, Shinozaki K Y, Chua N H. Nuclear proteins bind conserved elements in the abscisic acid-reponsive promoter of a rice rab gene[J]. Proc Natl Acad Sci USA, 1990, 97: 1406. 钱海丰;薛庆中.;激素对高羊茅愈伤组织诱导及其分化的影响[J]
Competitive protein binding assay indicates the level of cAMP is improved when CDCA is given by oral administration. 通过竞争性蛋白质结合分析法测得，鹅去氧胆酸经灌胃给药后能显著提高大白鼠气管组织中cAMP的含量。
Method H?3?cAMP was used in protein binding assay to determine the level of cAMP in bovine BTC. 方法运用蛋白竞争结合法用氚（H3）标记的环磷酸腺苷（adenosine3，5?cyclicmonphos?phate，cAMP）测定牛眼小梁细胞内cAMP的含量。
Methods: Activity of PKC was determined by using competitive protein binding method. 方法:应用竞争蛋白结合法检测PKC活性。
Drug protein binding changes involved in numerous factors in vivo may cause changes of pharmacokinetic parameters. 体内各种因素引起的药物与血浆蛋白结合的改变,可能导致相应的药代动力学参数变化。