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- Abstract: BACKGROUND: Gene promoter methylation is an epigenetic eent leading to gene silencing. 摘要:背景:基因启动子甲基化是一种可引起基因沉默的表观遗传事件。
- The frequency of p16 promoter methylation is higher in Dukes stages of C and D CRC (59%) than A and B CRC (20%)(p<0.05). p16基因启动子区甲基化在Dukes分期A、B和C、D期中发生率分别为20%25和59%25,差异显著(p<0.;05);
- Objective To investigate the protein expressions of DAPK gene and its promoter methylation status of lung cancer tissues in Yunnan tin miners. 目的探讨云锡矿工肺癌组织DAPK基因的蛋白表达及其甲基化异常。
- We will further investigate the relationship of histone modification and promoter methylation on the expression of TFPI-2. 今后,我们将在表观遗传层面对TFPI-2基因的修饰和相关组蛋白的修饰进行深入研究。
- Abstract BACKGROUND & AIM: We studied the expression and promoter methylation of CAGE gene in intracranial tumors in order to explore its potential use in tumor immunotherapy. 摘要 背景与目的: 检测颅脑肿瘤组织中CAGE基因的表达及启动子区甲基化情况,探讨将其用于肿瘤免疫治疗的可能性。
- Expression of the PTEN tumor suppressor is frequently lost in breast cancer in the absence of mutation or promoter methylation through as yet undetermined mechanisms. PTEN肿瘤抑制因子在乳腺癌中虽常呈失表达,但并不是通过基因突变或促进子甲基化而实现的,因此其失表达的机制还不清楚。
- BACKGROUND &AIM:We studied the expression and promoter methylation of CAGE gene in intracranial tumors in order to explore its potential use in tumor immunotherapy. 背景与目的:检测颅脑肿瘤组织中CAGE基因的表达及启动子区甲基化情况,探讨将其用于肿瘤免疫治疗的可能性。
- Objective To investigate the COX-2, hMLH1 and hMSH2 of genes promoter methylation and MSI frequency in 43 cases of human gastric carcinoma and normal tissues, and to evaluate the relationship between them and occurrence of gastric carcinoma. 目的检测临床手术切除43例胃癌及相应正常组织COX-2、hMLH1和hMSH2微卫星不稳定状态MSI及三种基因启动子甲基化情况,并进一步探讨它们与胃癌发生的关系。
- Promoter methylation of RASSF1A gene may be involved in the early-stage during thyroid tumorigenesis, and the similar change in P16INK4a gene is related to lymphatic metastasis of PTC. 5.甲状腺乳头状癌组织中RASSF1A基因启动子甲基化可能出现在甲状腺肿瘤发生的早期阶段,P16INK4a基因启动子甲基化在甲状腺乳头状癌的淋巴转移中发挥一定作用。
- Objective: To investigate the relationship between the characteristics of promoter methylation of RASSF1A gene in papillary thyroid carcinoma (PTC) and the clinical manifestation of PTC. 摘要目的:探讨甲状腺乳头状癌及癌旁组织中RASSF1A基因启动子甲基化改变的特点与临床特征的关系。
- Good humor is a promoter of friendship. 良好的幽默感能促进友谊。
- Relation between promoter methylation of E-cadherin gene and gastric and colorectal adenocarcinoma and its significance 上皮型钙黏素基因启动子甲基化与胃肠腺癌的关系及意义
- Mismatch Repair Gene Promoter Methylation and Expression in Hydatidiform Moles and the Malignant Transformation 错配修复基因启动子甲基化和蛋白表达在葡萄胎的发生及恶变中的作用
- Study on DAPK Gene Promoter Methylation in Lung Cancer among Yunnan Tin Miners and a Rat Model of Lung Cancer with Yunnan Tin Mineral Dust in F344 Rats DAPK基因启动子甲基化在云锡矿工肺癌及矿粉诱发F344大鼠肺癌中的检测研究
- Allene is an isomer of methyl acetylene. 丙二烯是甲基乙炔的一种异构体。
- He is the promoter of this campaign. 他是这次运动的推动者。
- Methylation of chromatin causes it to condense. 染色质甲基化后会出现凝缩。
- That fellow is a promoter of boxing events. 那人是拳击比赛的赞助人。
- The mechanism of methylation reaction is discussed. 对甲基化反应机理进行了讨论.
- Cheerfulness is the best promoter of health. 快乐最利于健康。