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He do not wear a coat in spite of the cool weather. 虽然天气寒冷，他没有穿外套。
Try to sleep in spite of the noise. 尽管有喧闹声也要设法睡著。
In spite of one or two minor mishaps everything was going swimmingly. 尽管遇到了一两件小小的不幸，一切都进行得很顺利。
I went shopping in spite of the rain. 尽管下雨，我还是出去买东西了。
In spite of our advice, he married above himself. 他不顾我们的劝告，同比自己地位高的人结了婚。
In spite of the bad weather, we went fishing. 我们不顾恶劣的天气而去钓鱼。
In spite of my efforts the boy remained passive. 尽管我努力，那男孩还是不起劲。
Over one's protest: in spite of one's protest A nuclear plant was built in the area over the farmers'protests. 一座核电厂不顾农民的抗议在这个地区建了起来。
He gave a mild answer, in spite of his annoyance. 他尽管已恼火，但回答得还是很和蔼。
In spite of the normal appetite, he lost 4 kg. in weight over a period of one year. 食欲正常，但体重却在一年之内减轻了4公斤。
He never gave himself up to pessimism in spite of difficulties. 尽管遇到困难他从没有消极悲观过。
A good harvest was obtained in spite of the drought. 尽管遭受干旱，还是获得了好收成。
He was as thin as a rake in spite of his enormous appetite. 虽然他食欲很大，却长得骨瘦如柴。
The artist painted on in spite of the other people's opposition. 那位艺术家不顾其他人的反对继续作画。
The Grand National will be run in spite of the bad weather. 尽管天气不好，一年一度的全国大马赛仍将举行。
The team must hang together in spite of their many losses. 尽管失败多次，这个队一定要同心协力，抱成一团。
In spite of vigilance a polar bear escape from the zoo. 尽管警戒很严，北极熊还是逃出了动物园。
He fail to lift the stone in spite of all his exertion. 他显然尽了全力，仍未能将此石头抬起。
She fail to unlock the safe in spite of all her exertion. 她虽然费尽力气，仍未能将那保险箱的锁打开。