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- Apoptosis of drug-resistant human ovarian cancer cell line COC_1/DDP induced by survivin antisense oligonucleotides. Survivin反义寡核苷酸诱导人卵巢癌耐药细胞株COC_1/DDP凋亡的实验研究
- Objective:To study the mechanism of sodium butyrate (NaB) on human ovarian cancer cell line 3AO. 目的 :研究丁酸钠逆转人卵巢癌 3AO细胞恶性表型的机制。
- Conclusion:The reconstituted SCID mouse model with human ovarian cancer cell line has been established successfully. 结论：免疫重建的荷人卵巢癌-SCID小鼠模型已初步建立成功。
- Survivin antisense oligonucleotides could effectively induce apoptosis of drug-resistant human ovarian cancer cell line COC1/DDP. survivin ASONs反义寡核苷酸能诱导人卵巢癌耐药细胞株COC1/DDP细胞凋亡 ,且效果显著
- Objective:To explore the molecular mechanism of topotecan-induced apoptosis in cisplatin-resistant human ovarian cancer cell line COC1/DDP. 目的探讨拓扑替康(TPT)诱导人卵巢癌顺铂耐药株COC1/DDP凋亡的内在分子机制。
- Methods: Human ovarian cancer cell line COC1 was cultured in medium containing ATRA in different concentrations in vitro. Cell proliferation inhibition was tested by MTT assay. 方法：选用人卵巢癌细胞株COC1进行体外培养，以不同浓度的ATRA处理COC1细胞，四甲基偶氮唑蓝（MTT）比色法检测细胞增殖抑制情况；
- Methods: Human ovarian cancer cell line COC1 was cultured in medium containing ATRA in different concentrations in vitro.Cell proliferation inhibition was tested by MTT assay. 方法：选用人卵巢癌细胞株COC1进行体外培养，以不同浓度的ATRA处理COC1细胞，四甲基偶氮唑蓝（MTT）比色法检测细胞增殖抑制情况；
- Abstract Objective ：To observe the effect of cisplatin, taxol and adriamycin on in vitro growth as well as the nature of cell death of human ovarian cancer cell line OVCAR-3. 摘要 目的 ：观察抗卵巢癌药物顺铂、紫杉醇和阿霉素对卵巢癌细胞系OVCAR-3体外生长和生存的影响并分析由它们所致的细胞死亡性质。
- Objective To investigate the inhibitory effects of rose roxburghii tratt juice(RRTJ) and morinda citrifolia juice(NoniJ) on the growth of human ovarian cancer cell line COC_2 in vitro. 目的探讨刺梨汁(RRTJ)、诺丽汁(Non iJ)及刺梨汁联合诺丽汁对卵巢癌细胞株COC2体外生长的抑制作用。
- Objective; To investigate the expressions of anti-apoptotic protein Bcl-XL,Bcl-2, cytochrome C and the caspase-3 activity in cisplatin-resistance human ovarian cancer cell line COC1/DDP and explore their correlation to the chemoresitance of COG1/DDP. 目的 探讨人卵巢癌顺铂耐药细胞株COC1/DDP中抗凋亡蛋白Bcl-XL、Bcl-2、细胞色素C的表达及半胱天冬氨酸蛋白酶-3(caspase-3)活性与人卵巢癌顺铂耐药的关系。
- ATRA can both inhibit proliferation and induce differentiation of human ovarian cancer cell line COC1.These results may provide an effective and novel approach for clinical treatment of human ovarian cancer. ATRA能明显抑制人卵巢癌细胞株COC1的生长增殖并诱导部分细胞向良性分化。
- Methods: The expressions of Bel-XL , Bcl-2, cytochrome C and caspase-3 activity were studied by RT-CR and Western blot in the cisplatin-resistant (COC1/DDP) and cisplatin-sensitive human ovarian cancer cell line (COC1) . 方法:采用RT-PCR和Western Blot分析人卵巢癌顺铂敏感细胞株COC1和顺铂耐药株COC1/DDP中Bcl-XL、Bcl-2、细胞色素C的表达和caspase-3的活性。
- Objective To investigate the cytotoxicity and proapoptotic activity of topotecan(TPT) on cisplatin-resistant human ovarian cancer cell lines COC1/DDP and its mocular mechanisms. 目的探讨拓扑替康(TPT)对人卵巢癌顺铂耐药细胞株COC1/DDP的杀伤和诱导凋亡活性及其作用机制。
- Effects of DOC-2 on proliferation of human ovarian cancer cell line TC-1 DOC-2对卵巢癌细胞TC-1增殖的影响
- Cloning of Expression Vector of Human Tissue Factor Gene and its Expression in Human Ovarian Cancer Cell Line 人组织因子基因表达载体的构建及其在人卵巢癌细胞系中的表达
- Isolation and Characterization of Human Ovarian Cancer Cell Line Subclones with Different Metastatic Potential 人卵巢癌细胞系具有不同转移潜能亚系的分离及体内和体外鉴定
- The anti-proliferating effects of different combination modes of DDP and 5-FU on human ovarian cancer cell line 3AO 顺铂、5-FU联合应用及联用方式对人卵巢癌细胞株生长的抑制作用
- Effect of DOC-2 (differentially expressed in ovarian cancer 2) on human ovarian cancer cell line DOC-2在卵巢癌细胞系中的表达及其生物学功能
- Effects of Survivin antisense RNA on the growth of human ovarian cancer cell line SKOV3 Survivin反义核酸对SKOV3细胞生长及Survivin基因表达的影响
- The impact of DOC-2 expression on the tumorigenesis of human ovarian cancer cell line(HO-8910) DOC-2对卵巢癌细胞HO-8910致瘤力的影响
