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- Preliminary data indicate that steviol may be activated to a mutagenic metabloite by human liver microsomes. 初步数据显示,甜菊醇可能经人体的肝脏微粒体活化成引致基因突变的代谢物。
- Based on metabolite analysis, several PAC-1 metabolic pathways in human liver microsomes were proposed. 结论 PAC-1在人肝微粒体系中的代谢途径为脱苄基化和羟基化。
- The mean (MEGX+GX)/LDC ratio was 3 2 8. CONCLUSIONThe (MEGX+GX)/LDC ratio can be used to evaluate C YP3A activity of human liver microsomes. 结论 (MEGX +GX) /LDC可用来估算人肝微粒体CYP3A的活性。
- AIM A HPLC method for the determination of cilnidipine and its major metabolite was developed and the kinetics of its metabolism in human liver microsomes was studied. 目的建立人肝微粒体中西尼地平及其脱氢代谢物的HPLC测定法,并用本法研究西尼地平在人肝微粒体中代谢的动力学。
- Methods In this study, a liquid chromatography-time of flight mass spectrometric method was developed and applied to characterize the metabolites of PAC-1 after incubation with human liver microsomes. 方法 在一定的人肝微粒体浓度中加入药物,温孵后,采用液相色谱-飞行时间质谱法对孵化体系中的代谢产物进行分析。
- human liver microsomes 人肝脏微粒体
- Liu ZQ, Cheng ZN, Wang W, Wang LS, Ou-Yang DS, Zhou HH Determination of fluoxetine and its metabolite norfluoxetine in human liver microsomes by reversed-phase HPLC in vipo Acta Pharamcol Sin 2000; 欧阳冬生、黄松林、王伟、王丹、周宏灏国产盐酸曲马多栓的人体药代动力学和相对生物利用度,中国临床药理学杂志,2000;
- Preparation of monoclonal antibody against human liver microsome proteins 抗人肝微粒体蛋白单克隆抗体细胞系的建立及鉴定
- Human liver kidney microsome autoantibody,LKM ... 人抗肝肾微粒体抗体(LKM)试剂盒;
- Study on activity level and kinetics characteristic of human liver microsome ethylmorphine N-demethylase 成人肝细胞微粒体乙基吗啡N-脱甲基酶活性及酶动力学研究
- Keywords daidzein;human liver microsome;hydroxylation metabolism;cytochrome P450 (CYP1A2); 大豆苷元;人肝微粒体;羟基化代谢;细胞色素P450(CYP1A2);
- The correlation between peak area of a metabolite and original concentration of Nef in rat liver microsomes solution was significant( r =0.993). 温孵液中代谢产物生成的量与底物Nef的浓度具有良好的相关性(r=0.;993);
- IN VITRO METABOLIC STUDIES OF THE NOVEL ANTI-ANXIETIC DRUG AF-5 AND ITS METABOLITES IN HUMAN LIVER MICROSOME INCUBATION SYSTEM 抗焦虑新药AF-5及其代谢物在人肝微粒体体外温孵体系中代谢研究
- DETERMINATION OF NIMODIPINE AND ITS DEHYDROGENATION METABOLITE IN HUMAN LIVER MICROSOME BY HPLC AND ITS METABOLIZING KINETICS 人肝微粒体中尼莫地平及其脱氢代谢物的HPLC测定法及代谢动力学
- And it can induce human liver cancer,carcinoma of tesis esophagus cancer. 目前的检测方法有:高效液相色谱、气相色谱、薄层色谱、无毒检测体系和免疫学检测。
- human liver microsome 人肝微粒体
- human liver microsome proteins 人肝微粒体蛋白
- Previous studies have identified CYP1 A2 and CYP3A4 as the major enzymes for AFB_1 activation in human liver. 但由于CYP1A2主要在肝脏中表达,而在肺脏中甚微,因而至今还不清楚在人肺脏中究竟哪些CYPs在AFB1的代谢活化中发挥关键性的作用。
- The human liver can regenerate up to 50 percent of its mass within weeks, just as a salamander regrows a severed tail. 人类的肝脏也会像蝾螈长回断尾一般,在数周内重生50%25;
- A segmenting algorithm for the human liver MDCT medical images based on small region growing is presented. 摘要提出了一种基于小区域增长的分割算法对人体肝脏的MDCT医学图像进行分割。