The conformational change courses in the different concentrations of guanidine have been to be first order reactions. 同时还测定了不同浓度胍溶液中人肌酶的失活与构象变化的速度常数。
This could give reason for aggregate formation of GAPDH in the presence of low concentration guanidine hydrochloride. 说明在低胍作用下，酶分子发生的构象变化，导致天然态内埋疏水面的暴露，暴露的疏水面间的相互作用是形成聚合的主要原因。
美
['gwænədiːn]
