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- The AR protein is composed of four domains,the N-terminal domain(NTD)or transactivation domain,the DNA binding domain(DBD),the flexible hinge region and the ligand binding domain(LBD). AR的配体,雄激素是主要的内源性性类固醇激素,而更多的研究却表明雄激素在鱼类性分化过程中不起作用,AR在此过程中的作用尚不清楚。
- DNA binding domain DBD
- DNA binding domain(DBD) DNA结合域, DNA结合区
- Zinc-finger DNA binding domain 锌指DNA结合域
- Cloning, sequence and Expression analysis of a zinc finger protein gene in wheat. 小麦锌指蛋白基因克隆、序列与表达分析。
- It codes for a large C2H2 type zinc finger protein which may act as a transcriptionfactor. PEG3基因编码一个高分子量的C2H2型锌指蛋白,该蛋白可能是一种转录因子。
- It is firstly characterized for the SCAN-(C2H2)X genes to truncate the zinc finger domains at the carboxyl terminus. 我们鉴定了SCAN-(C2H2)X基因会在其羧基端截除锌指结构域。
- He used a" zinc finger nuclease " Protein (zinc finger protein), stripping to T-cell surface of the CCR5 gene. 他采用一种名为“锌指核酸酶”的蛋白质(即锌指蛋白),来剥离T细胞表层的CCR5基因。
- This study reports cloning and expression analysis of a novel human zinc finger protein ZNF18 cDNA. 本文报道了克隆和表达分析人类新的锌指蛋白基因ZNF18。
- The structure and expression pattern implies it migh t be a DNA binding transcription regulator. 它的结构和表达特征预示着它编码的是一个具DNA结合功能的转录调控因子.
- The full-length cDNA of OsAGAP consisted of 1328 nucleotides. The protein encoded was composed by 320 amino acids and included two conserved domains: zinc finger domain and C2 domain. OsAGAP的cDNA全长为1328bp,编码的蛋白由320个氨基酸组成,含有两个保守结构域:锌指结构域和C2结构域。
- EMSA showed that stimulation of HSC by Aldo markedly increased AP-1 DNA binding activity. Aldo可增强HSC的AP-1的DNA结合活性。
- The autoimmune regulator(AIRE) showned DNA binding activity and transcrip-tional transactivation potential. 自身免疫调节因子(autoimmune regulator,AIRE)是一种具有转录活化潜能的DNA结合蛋白。
- A typical BIR motif and a BIR like motif were found in HaSNPV IAP3 protein. In the C terminal a typical RING zinc finger motif was found. HaSNPVIAP3蛋白的N端发现有一个典型的BIR结构和一个类BIR结构 ,C端有一个典型的RING锌指结构。
- Sequence differences in the ligand binding domain of PXR serve as the molecular basis for the species difference in CYP3A induction. 化学物通过PXR调节CYP3A的表达可能是影响化学物体内代谢的一条重要途径。
- Many zinc finger genes encoding the SCAN domains are clustered in human genome, e.g. 17p12-13 (ZNF18, ZNF29, ZNF62 and zfp3). 一些编码SCAN结构域的锌指基因在人类基因组中常成簇分布,例如17p12-13的ZNF18, ZNF29, ZNF62和zfp3四个基因。
- There were DNA binding proteins in the SR of rats, and the molecular weight was 78 000 and 60 000 dalton. 大鼠膈肌SR上存在非序列依赖性DNA结合蛋白 ,相对分子质量分别为 6 0 0 0 0道尔顿和 780 0 0道尔顿。
- When they exposed tobacco cells to the zinc finger nucleases, they also added a version of that gene that enhances herbicide resistance. 他们在使烟草细胞接触锌指核酸酶之外,也添加了可增强抗除草剂特性的基因片段。
- These oligonucleotides contain consensus DNA binding sites for individual sequence-specific transcription factors. 这些寡核苷酸共同学列是单个序列特异性的转录因子DNA结合位点。
- OBJECTIVE: To construct a zinc finger protein 403 (Znf403) prokaryotic vector and observe its expression in eucaryotic cells. 目的:构建锌指蛋白403基因原核表达载体,观察其在真核细胞的表达情况。