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- TH阳性神经元 TH-ir neuron
- 免疫组化检测,成功模型光镜下分别计数双侧黑质TH阳性神经元,损毁侧黑质TH阳性神经元占正常侧的3.8%,即毁损侧TH阳性神经元减少96.2%。 The immunohistochemical staining showed a significant reduction(in 3.8%25)of TH-positive neurons in the 6-OHDA injection side compared with the opposite side.
- 此外,我们还发现一种特异性兴奋PI-linked多巴胺受体的化合物SKF83959,激活PLC-IP_3-Ca~(2+)下游信号转导通路,引起胞内Ca~(2+)浓度明显上升,促进FGF-2蛋白合成和分泌,有效地保护TH阳性神经元的存活。 APO failed toinduce FGF-2 upregulation in astrocytes transfected with pEGFP-RGS2.In this study we characterized SKF83959, a selective agonist for the PI-linkedD1 liked DAR, stimulated IP3 hydrolysis and increased intracellular Ca2+. Via thismolecular mechanism, SKF83959 induced FGF-2 biosynthesis and secretion inastrocytes, thereby promoting survival of TH positive neurons.
- 在颈上神经节内发现了TH阳性细胞,细胞体为圆形或卵圆形。 TH免疫反应亦见于小强荧光细胞(SIF cells)。 TH-positive cells are observed in the SCG and the cell bodies are round or oval, TH-positive cells are also observed in SIF cells(small intensely fluorescent cells).
- 无论是实验组还是对照组,L3-L5 DRG中SP阳性神经元的比例均高于L1和L2中的比例。 And the ratio of SP-ir neurons in L1 and L2 DRGs was significantly lower than those in L3-5 DRGs (P<0.001).
- 与PBS对照侧相比,LPS注入黑质导致TH阳性细胞数下降至38%; SB203580预处理可以显著增加TH+细胞数达63%(P<0.05)。 Compared with PBS control side , TH-positive neurons inthe SNdecreased by 68%25, TH-positive neurons in the SN preconditioned by specific inhibitor SB203580 increased significantly .
- 辣椒素对大鼠三叉神经节一氧化氮合酶阳性神经元的影响 Effect of capsaicin on nitric oxide synthase positive neurons in trigeminal ganglion of rats
- 汞中毒对大鼠学习记忆能力和海马NADPH-d阳性神经元的影响 The research on Learning Memory and NADPH-d Positive Neurons in Hippocampus of Chronic Mercury-exposed Rats
- 6-OHDA注射24天后,大鼠黑质TH阳性细胞大部分消失,但在腹腔注射BBA后,黑质TH阳性细胞存活明显增多,其中10 mg·kg~(-1)·d~(-1)的BBA的作用最强(P<0.01); In 6-OHDA-lesioned SN, most TH-positive neurons disappeared, while in BBA-treated rats there were more survival neurous observed. The neuroprotective action of BBA was most potent at the dose of 10 mg. kg~(-1).
- 阳性神经元 positive neurons
- NOS阳性神经元 NOS positive neurons
- 免疫阳性神经元 immunopositive neuron
- AChE阳性神经元 AChE positive neurons
- ChAT阳性神经元 ChAT-positive neurons
- Fos免疫阳性神经元 Fos-like immunoreactive neuron
- 大鼠尾壳核头部一氧化氮合酶阳性神经元区域性分布和脑缺血后变化 THE DISTRIBUTION AND ISCHEMIA-INDUCED CHANGES OF NITRIC OXIDE SYNTHASE POSITIVE NEURONS IN THE HEAD OF NUCLEUS CAUDATUS PUTAMEN IN RATS
- 局部皮质内注射海仁酸对皮质和海马一氧化氮合酶阳性神经元的影响。 Local injection of kainic acid causes widespread degeneration of NADPH-d neurons and induction of NADPH-d in neurons, endothelial cells and reactive astrocytes.
- 一氧化氮合酶阳性神经元 NOS-positive neuron
- NGF诱导大鼠胚脑皮层和隔区神经干细胞向神经元和AChE阳性神经元分化的作用 Effects of NGF on inducing the rat embryonic neural stem cells derived from cortex and septal region to differentiate into neurons and AChE positive neurons in vitro
- 促肾上腺皮质激素及电针对甲醛痛敏大鼠脊髓一氧化氮合成酶阳性神经元的影响 Effects of adrenocorticotropic hormone and electroacupuncture on formalin- induced NOS-positive neurons in the spinal cord of rats
