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- It is used not only in treatment of depression, but also in treatment of stress urinary incontinence and diabetic peripheral neuropathic pain. 目前发现不仅可以治疗抑郁症，还可用于治疗压力性尿失禁与糖尿病周围神经病性疼痛。
- The SCS response rate in peripheral neuropathic pain has a relationship with the degree of nerve injury: the less nerve injured allodynia is more likely to be treated by SCS. 4. 本研究的主要创新点是： 1.;制备了的高成功率的胫神经切断模型（TA），并首次证实SCS可以有效的缓解该模型的机械性痛觉超敏，为进一步研究神经源性疼痛的发病机理以及SCS的作用机制奠定了基础。
- Clinically, it has been used to treat peripheral neuropathic pain associated with diabetic peripheral neuropathy (DPN) , postherpetic neuralgia (PHN) and as an adjunctive treatment for epilepsy. 临床用于治疗外周神经痛、糖尿病性外周神经病(DPN)引起的疼痛、疱疹后神经痛(PHN)及部分癫痫发作的辅助治疗。
- Peripheral neuropathic pain 外周神经源性疼痛
- Development of Neuropathic Pain in the Rat Spared Nerve Injury Model Is Not Prevented by a Peripheral Nerve Block Suter MR, et al. 大鼠小神经损伤模型中病理性神经痛的发展不能通过外周神经阻滞防止。
- Moreover, studies suggest that such agents could well dampen inappropriate hyperactivity by injured peripheral nerves and thus might relieve some neuropathic pain. 有研究显示，这种药物可降低受损周边神经的过度反应，而可能消除一些神经痛。
- Etiology and treatment of neuropathic pain in the primary focus of management for many patients with painful peripheral neuropathy. 神经痛的病因和治疗在疼痛性周围神经病患者处理中是最关键的。
- Gabapentin Acts within the Locus Coeruleus to Alleviate Neuropathic Pain. 加巴喷丁作用于蓝斑核可减轻神经性疼痛。
- Object: To observe the clinic effect of neurotropin for the patients with peripheral neuropathic changes. 目的:观察神经妥乐平治疗周围神经病变的临床效果。
- This study suggests new aenues to manage neuropathic pain in this setting. 这项研究对治疗神经性疼痛提供了一条新途径。”
- The main side effects were gastrointestinal disturbance, peripheral neuropath... 主要的毒副作用为胃肠道反应、神经毒性及脱发。
- It also be associated with apoptosis in peripheral and central nerve systems.The further study on the mechanism of diabetic peripheral neuropath... 对糖尿病周围神经病变机制进一步的研究将为其预防和治疗提供更好的理论基础。
- BACKGROUND: Many animal models can be used to study the underlying pathophysiological mechanisms of neuropathic pain. 背景：很多动物模型被用来研究神经性疼痛的基础病理生理学机制。
- However, neurontin (gabapentin) and other anti-epileptic drug may reduce both spasms and neuropathic pain. 然而，加巴（加巴喷丁）和其他抗癫痫药物可减少痉挛和神经性疼痛。
- There were no significant functional changes in any patients and no neuropathic pain. 患者没有出现明显功能改变和神经性疼痛。
- Objective: Mutual prodrugs of gabapentin and pergabalin were synthesized for relieving neuropathic pain. 目的:合成具有抗神经病理性疼痛的加巴喷丁和普瑞巴林的互联体前药化合物。
- Neuropathic pain refers to pain that originates from pathology of the nervous system. 神经病理痛是指由中枢或外周神经系统损伤或疾病引起的疼痛综合征。
- Drugs to treat neuropathic pain are usually of some benefit, including gabapentin, carbamazepine, and amitriptyline. 加巴喷丁、卡马西平、阿米替林等药物治疗神经性疼痛疗效常较好。
- Sodium channel of dorsal root ganglion (DRG) plays an important role in the mechanisms of neuropathic pain. 摘要脊髓背根神经节的钠通道与神经性疼痛的形成有密切的关系。
- Our findings show that this may cause neuroinflammation in the dorsal root ganglion and neuropathic pain. 我们的研究显示这可能导致背角神经节的神经炎症和神经病理性痛。
