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- Objective To show the relationship between the expression of hcf family and neuron apoptosis. 目的探索神经细胞凋亡与bcl-2家族基因表达的关系。
- Ginkgo biloba extract injection may alleviate the neuron apoptosis by increasing HSP 70 expression. 银杏叶提取物可能通过上调缺血缺氧后热休克蛋白70的表达减少神经细胞凋亡。
- The main reason of neuron apoptosis was the result of NTFs reduced after nerve ischemia. 神经缺血导致相关神经元胞体中神经营养因子含量减少,是神经元凋亡的主要原因。
- But there was significant temporal difference in the ultrastructural alteration.The axonal degeneration appeared earlier than neurons apoptosis. 但在超微结构变化上存在时间差异性,轴突微管的损伤发生较早,而典型的神经元凋亡改变出现较晚。
- We study the effect of scalp acupuncture on expression of GDNF, CNTF in spinal motor neurons and neurons apoptosis after PN nerve injured. 并从对相应节段脊髓运动神经元GDNF、CNTF表达的影响和对运动神经元凋亡的影响方面,探讨头针的作用机制。
- Conclusion Direct-current stimu lation may have intervention effects on spinal cord neuron apoptosis after sciatic nerve transection. 结论直流电刺激对坐骨神经横断引起的脊髓运动神经元凋亡具有防治作用。
- Objective To observe the effect of vitamin E(VE) supplementation on antioxidation capacity and hippocampus neuron apoptosis in senile female rats. 摘要目的探讨维生素E(VE)对老年雌性大鼠抗氧化作用和海马神经元凋亡调节作用。
- Here, we used a model of ischemia-reperfusion injury and found that EGF-A exposure resulted in a dose-dependent reduction in retinal neuron apoptosis. 在研究中,我们运用一种缺血-再灌注损伤模型发现EGF-A出现导致视网膜神经元凋亡成剂量依赖性的减少。
- Tin-protoporphyrin inhibited HO-1-mRNA, and increased neuron apoptosis and decreased neuron viability(vs group D12,P<0.05 or P<0.01). T组PERK1/2和PP90RSK蛋白表达变化不明显(vsD12组;P>0.;05);HO-1-mRNA表达降低;神经元存活率降低、神经元凋亡率增加(vsD12组;P<0
- The nNOS and iNOS expression and the neuron apoptosis of the Imi group were significantly decreased compared with those of the IRgroup(P<0.01). 米帕明保护组神经细胞nNOS、iNOS的表达和凋亡神经细胞数明显低于缺血再灌组(P<0.;01)。
- Objective: To observe the change of the content of NO during neuron apoptosis after the oppression of cauda equina nerve. 摘要目的:探讨马尾神经压迫后NO含量变化在细胞凋亡中的作用。
- Results Desflurane enhanced expression of HO-1-mRNA, PERK1/2 and PP90RSK, meanwhile increased neuron viability and decreased neuron apoptosis(vs group C and I/R,P<0.01). D12组PERK1/2和PP90RSK蛋白表达增加;HO-1-mRNA表达增加;神经元存活率增加、神经元凋亡率降低(vsI/R组或D6组;P<0.;01或P<0
- Facial nerve injury can lead to high pressure facial nerve and motoneuron apoptosis and caspase signaling pathway may be the final executor of neuron apoptosis. 面神经损伤将导致的面神经内压升高、运动神经元凋亡,caspase信号通路可能是神经元凋亡的最终执行者。
- Cultured CGC are widely used as a model system for studying neuronal apoptosis. 小脑颗粒细胞培养可作为模型系统而广泛用于研究神经元的凋亡。
- The pathophysiological mechanisms of ischemic cerebral injury involved in the release of excitatory amino acids, depolarization about the infarction, inflammatory reaction and neuron apoptosis. 缺血性脑损伤的病理生理机制包括兴奋性氨基酸的释放、梗死灶周围去极化、炎症反应及神经元凋亡等。
- These results indicated that glutamate induced apoptosis on cultured cerebellar granule neurons and phospho-C-JUN might not be involved in the neuronal apoptosis. 上述结果提示,谷氨酸诱导小脑颗粒神经元凋亡,磷酸化C-JUN不参与谷氨酸诱导的大鼠小脑颗粒神经元凋亡。
- To detect cytoactive by MTT and LDH, and neuronal apoptosis by TdT-mediated dUTP-biotin nick end labeling (TUNEL). 应用MTT、LDH检测细胞活性,原位末端标记(TUNEL)方法检测细胞凋亡。
- Conclusion: PKC inhibitor could prevent neuronal apoptosis induced by cerebral ischemia/reperfusion. 结论:灯盏花注射液对脑缺血/再灌流导致神经元凋亡有防治作用。
- Thus, cerebral NADPH oxidase activation preceded cerebral inflammation and neuronal apoptosis. 因此脑NADPH氧化酶的活化早于脑部炎症和神经元的凋亡。
- Conclusion The interrelantion of calcium and PKC induced neuronal apoptosis afte... 结论脑缺血再灌注后PKC和钙相互作用共同促进了神经细胞的凋亡。