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In recent years, in view of increasing drug resistance problems, studing new anti-H.pylori agent becomes important. 近年来,由于幽门螺杆菌耐药性增加,研究新的抗幽门螺杆菌药物成为一项重要研究课题。
Increased drug resistance 耐药性增加
Kirby-Bauer was used to detect the drug resistance. 采用kirby -Bauer法检测其耐药性。
The tolerance of bone marrow to Ara C was remarkably increased after transfected by drug resistance gene. 耐药基因转染后小鼠骨髓对阿糖胞苷的耐受明显增加。
The disease has increased with the spread of ADIS and drug resistance forms of tuberculosis. 随着Adis疾病的蔓延,形成抗药性肺结核。
K562/ADM had no drug resistance to As2O3 and matrine. 非细胞毒性剂量的三氧化二砷和苦参碱均可部分逆转有多药耐药表型的细胞株K562/ADM对阿霉素的耐药J险，二者联合应用效果优于单独应用，具有协同作用。
Such misuse of medicines can lead to drug resistance. 这样滥用药物会导致抗药性。
To develop effective combination of drug resistance modulators. 目的:寻找有效的多药耐药联合逆转剂。
Results The drug resistance of 57 strains of Enterobacter cloacae increased at differently extent for common used antibiotics.While these strains only sensitive to Imipenem. 结果57株阴沟肠杆菌对临床常用抗生素耐药性均不同程度增加,只对亚胺培南敏感。
Drug resistance surveillance of pulmonary tuberculosis in Jiaxing City. 嘉兴市肺结核病耐药监测。
Study on infections and drug resistance of mycoplasma in female vaginalis. 株解脲支原体耐药分析。
And similar to penicillin, many bacteria also have had a sulfa drug resistance. 和青霉素类似，很多细菌也对磺胺产生了耐药性。
IFN combined with ATRA can partially revert drug resistance in MR2 cell. 2：IFN 联合ATRA能够部分逆转MR2细胞耐药。
Drug resistance is the main restriction factor for clinical usage of taxanes. 耐药是影响紫杉类药物临床疗效的重要因素。
In summary, increased infection risks and drug-mediated immunomodulation increase drug abusers’ susceptibility to infectious pathogens. 总之, 感染机会增加以及药物介导的免疫调节作用增加了药物滥用者对机会性感染病原体的易感性。
Overexpression or functional abnormality of membrane drug transport proteins of ATP-binding cassette(ABC)family which results in an increased drug efflux,could be one of the main mechanisms. 其中,肿瘤细胞膜上ATP结合盒(ABC)转运蛋白的表达或功能异常是肿瘤细胞产生MDR的重要机制之一。
Verapamil increased the intracellular drug accumulation, and then obviously reversed the drug resistance to DNR, VCR, MIT, HHT, and VP 16 in K562/D cells, but not in the sensitive cells (K562/S). 异搏定使 K 5 6 2 / D细胞内药物积聚增加 ,明显地逆转了 K5 6 2 / D细胞对 DNR、VCR、MIT、HHT、VP- 16的耐药性 ,而对敏感细胞 K5 6 2 / S的耐药性无影响。
If the bacteria glow, it means they are drug resistant. 如果细菌发光，这意味着它们具有耐药性。
It seems likely that the drug resistance is caused by permeability changes rather than enzyme deficiency. 抗药性似乎是由渗透性改变而不是酶缺损而引起的。
Drug resistance,dustproof,seamless safety,hyguiene,non-toxic,odurless,easy to clean,goodinsulation,wear resistance. 耐药品性佳、防尘、平滑无接缝、安全、卫生、无毒、无臭、易清洁维护、绝缘、耐磨。