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- The AR protein is composed of four domains,the N-terminal domain(NTD)or transactivation domain,the DNA binding domain(DBD),the flexible hinge region and the ligand binding domain(LBD). AR的配体,雄激素是主要的内源性性类固醇激素,而更多的研究却表明雄激素在鱼类性分化过程中不起作用,AR在此过程中的作用尚不清楚。
- DNA binding domain(DBD) DNA结合域, DNA结合区
- DNA binding domain DBD
- Zinc-finger DNA binding domain 锌指DNA结合域
- The structure and expression pattern implies it migh t be a DNA binding transcription regulator. 它的结构和表达特征预示着它编码的是一个具DNA结合功能的转录调控因子.
- EMSA showed that stimulation of HSC by Aldo markedly increased AP-1 DNA binding activity. Aldo可增强HSC的AP-1的DNA结合活性。
- Sequence differences in the ligand binding domain of PXR serve as the molecular basis for the species difference in CYP3A induction. 化学物通过PXR调节CYP3A的表达可能是影响化学物体内代谢的一条重要途径。
- The autoimmune regulator(AIRE) showned DNA binding activity and transcrip-tional transactivation potential. 自身免疫调节因子(autoimmune regulator,AIRE)是一种具有转录活化潜能的DNA结合蛋白。
- There were DNA binding proteins in the SR of rats, and the molecular weight was 78 000 and 60 000 dalton. 大鼠膈肌SR上存在非序列依赖性DNA结合蛋白 ,相对分子质量分别为 6 0 0 0 0道尔顿和 780 0 0道尔顿。
- These oligonucleotides contain consensus DNA binding sites for individual sequence-specific transcription factors. 这些寡核苷酸共同学列是单个序列特异性的转录因子DNA结合位点。
- This paper reviewed and discussed the mechanism of cellulase hydrolysis, and structures and functions of cellulase catalytic domain and cellulose binding domain. 主要探讨了纤维素酶水解纤维素的作用机理及纤维素酶分子催化区和吸附区的结构和功能。
- The autoimmune regulator (AIRE) showned DNA binding activity and transcriptional transactivation potential. 自身免疫调节因子(autoimmune regulator, AIRE)是一种具有转录活化潜能的DNA结合蛋白。
- DNA binding activity of transduction factor and transcription activator 3 between the two groups was similar ?P > 0.05?. 两组之间转导子和转录激活子3DNA结合活性接近(P>0.;05)。
- Telomeric proteins is composed of double DNA binding protein, single DNA binding protein and telomeric associated proteins. 端粒结合蛋白直接保护端粒DNA,端粒相关蛋白通过与端粒结合蛋白的相互作用间接影响端粒的功能。
- All the results indicated that the structures of amino acid bridge in the ligands may affect the DNA binding and cleavage ability. 研究结果表明氨基酸桥对于配体的DNA键合及裂解能力的有不同影响。
- In the context of identifying DNA binding motifs, using inferred transcription rates leads to more significant findings than those based on transcript amounts. 我们发现,对于共调控基因,比较直接用转录产物量,运用转录率可以提高它们的相关性。
- SRY represents a transcription factor belonging to the superfamily of genes sharing the HMG-box motif (high-mobility group-box), which acts as DNA binding region. SRY基因是一种转录因子，属于带有高迁移率族蛋白家族，该家族成员的包含能与DNA结合的HMG盒基序。
- As leucine zipper is a basic DNA binding motif of many known transcription factors, we examined the transcriptional function of the TCP10L using dual luciferase assay system. 本研究的结果进一步加深了对人体MT基因结构与功能的认识，也为阐明HCC发生的分子机制提供了有重要价值的资料。
- Methyl-CpG binding domain protein 1 甲基化CpG结合域蛋白1
- ligand binding domain cDNAof porcine β3 猪β3LBD基因
