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- This review focuses on the role and state-of-the-art advancements of costimulatory signals in ITP. 本文将就共刺激信号在ITP发病机制中的作用及其研究进展作一综述。
- If antigen present cells (APCs) provide MHC-peptides only, do not present costimulatory signals such as CD80 and CD86 to T lymphocytes at the same time, T lymphocytes will became anergy, immune tolerance will be induced. 如果抗原提呈细胞(antigen present cell,APC)只提供MHC-抗原肽复合物而不提供CD80、CD86等共刺激信号,将使淋巴细胞无能,诱导免疫耐受。
- The costimulatory signal mediated by 4-1BB molecule could mainly induce the proliferative response of CD8 + T cells, while that mediated by CD28 molecule could induce the activation of CD4 + T cells mainly. 4 1BB分子所介导的协同刺激信号 ,在CD8+ T细胞活化及增殖中发挥了更为重要的作用 ; 而CD2 8分子所介导的协同刺激信号则更有利于CD4 + T细胞的活化
- Blockage of costimulatory signal CD86 at the early stage of gestation can induce the reduction of the ratio of MMP-9/TIMP-3 by some mechanisms and reduce the embryo resorption rate in the abortion-prone model to that of normal pregnant level. 在妊娠早期阻断CD86协同刺激分子能够通过某些机制诱导自然流产鼠MMP-9/TIMP-3的比值降低并且降低自然流产模型的胚胎吸收率,使模型组的胚胎吸收率恢复至正常妊娠水平。
- Keywords OX40L;costimulatory signals;hybridoma;monoclonal antibody;leukemia; 共刺激信号;杂交瘤;单克隆抗体;白血病;
- Keywords 4-1BBL;Monoclonal antibody;Costimulatory signals;Hybridoma; 单克隆抗体;共刺激信号;杂交瘤;
- Preparation of the agonist/antagonist monoclonal antibodies against B7 and CD28 molecules and analysis of their effects on costimulatory signals transduction B7:CD28激发/拮抗型单抗的研制及其在共刺激信号传导中的调节作用研究
- A red light is usually a signal of danger. 红灯通常是危险的信号。
- Signals control each section of the railway track. 各种信号控制着铁路轨道的每个部分。
- Inducing peripheral materno-fetal immuno-tolerance by blockade of costimulatory signal at early stage of gestation of the abortion-prone murine model 妊娠早期阻断协同刺激分子诱导自然流产模型孕鼠脾脏细胞母-胎免疫耐受的研究
- Development of laboratory animal research of inducing transplantation immunity tolerance by blockading the costimulatory signal pathways 关于阻断共刺激通路诱导移植免疫耐受的实验动物研究进展
- I stood watching for the signal to change to green. 我站着等待交通信号转为绿灯。
- Let's set the clock by the radio time signal. 咱们照着收音机的报时信号把钟对一对。
- 4-1BB molecule could provide a costimulatory signal for activation and proliferation of CD4 + T cells and CD8 + T cells. 4 1BB分子可在CD4 + T细胞和CD8+ T细胞的活化、增殖中提供协同刺激信号。
- A period signals the end of a sentence. 句号表示一个句子结束了。
- A red lamp is often a danger signal. 红灯常常是危险的信号。
- A reflected signal on a communication channel. 一种在通信信道上反射回来的信号。
- The lighthouse flashes signals twice a minute. 灯塔每一分钟发出两次信号。
- The rise in prices was a signal for rebellion. 物价上涨引起了叛乱。
- The ship's radio sent out signals for help. 轮船上的无线电发出求助信号。