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- CD11/CD18 CD11/CD18
- CD18基因 CD18 gene
- CD11b／CD18 CD11b/CD18
- CD11a/CD18 CD11 a/CD18
- CD11b/CD18 CD11b/CD18
- CD11c／CD18 CD11c/CD18
- CD18淋巴细胞抗原 Lymphocyte antigen CD18
- 缺血预适应阻抑犬冠状窦血中性粒细胞CD11b/CD18的表达 Ischemic preconditioning attenuates the expression of neutrophils CD 11b/CD 18 in coronary sinus blood of dog
- 冠心病人血浆可溶性细胞粘附分子和白细胞CD18表达的动态变化 The Diurnal Variation of Plasma Soluble Cell Adhesive Molecule and Leukocyte CD18 Expression in Patients with Coronary Heart Disease
- CD11/CD18介导PMN－EC粘附在烧伤早期PMN损伤血管内皮细胞中的作用 Study of the effects of CD11/CD18-mediated PMN-EC adhesion on PMNinduced EC damages in the early stage postburn in vitro
- 灯盏细辛注射液对急性脑梗死患者血清粘附分子sICAM-1和CD11b/CD18的影响 Effect of Erigeron Injection on Expresions of Adhesion molecules CD11b/CD18 and Solution Cell Adhesion Molecule-1 in Peripheral Blood of Patients with Acute Cerebral Infarction(ACI)
- 目的：探讨烧伤血清作用下中性粒细胞CD11/CD18和内皮细胞ICAM－1表达的变化。 Objective: To observe the changes of expression of CD11/CD18 on polymorphonuclear neutrophils (PMNs) and ICAM-1 on endothelial cells (ECs) under the stimulation of burn serum.
- 肺部感染患者外周血中性粒细胞黏附分子CD11b CD18髓过氧化物酶的变化及临床意义 Changes of adhering molecules CD11b,CD18,myeloperoxidase(MPO) expression of the neutrophil in peripheral blood of pneumonia patients
- ACS患者血清E 选择素水平、中性粒细胞和单核细胞膜CD11b/CD18的表达增加与斑块不稳定性有关 The serum levels of soluble E-selectin and expression of CD11b/CD18 on neutrophils and monocytes in patients with ACS are related with unstability of plaques.
- 结果发现：CD18的表达为PMN快相增加粘附力的主要分子基础，而ELAM－1、ICAM－1则为VEC慢相增加粘附力的主要分子基础。 It was found that the main molecular basis of the rapid increase of PMN adhesive ability was CDI8 expression and that of the delayed increase of VEC adhesive ability was the expression of either ELAM-1 or ICAM-1.
- 提示：烧伤血清可剌激PMN和EC分别表达CD11a/CD18、CD11b/CD18和ICAM－1，从而加强PMN－EC粘附，在烧伤后PMN－EC粘附中起重要作用 The results suggested that burnt serum could enhance adhesive force between PMN and EC, stimulate expressions of CD11a/CD18,CD11b/CD18 and ICAM?1.Therefore,burnt serum played a great role in PMN?EC adhesion after burn injury. CD11a/CD18, CD11b/CD18 and ICAM?1 were the molecular base of PMN?EC adhesion.
- 丹参能降低黏附分子 CD11a/ CD18、CD11b/ CD18表达 ,抑制 PMN EC黏附 ,改善微循环及减轻 PMN EC黏附所致的组织损伤 ,有助于 AP的早期治疗。 Salvia miltiorrhiza can lower the CD11a/CD18,CD11b/CD18 expression, inhibit PMNEC adhesion, improve the microcirculation, ease the tissue damage produced by PMNEC adhesion and help the AP treatment in the early period.
- 严重烧伤能使外周血PMNCD11b/CD18表达明显增高，CD11b/CD18不但介导基础状态下的PMN粘附，更是介导烧伤后引起的大量PMN与PMEC粘附的主要分子。 Severe burn could induce the expression of PMN CD11b/CD18 which may be the main adhesion molecule participating in the increasing PMN adhesion to EC due to severe burns.
- 方法:采用DNA重组技术构建真核表达质粒pTRE-Tight-CFP-CD11b和pTRE-Tight-YFP-CD18(CD11b和CD18是Mac-1的两个亚基),通过脂质体介导共转染CHO细胞,用荧光显微镜观察转染后阳性细胞; Methods: The eukaryotic expression vectors pTRE-Tight-CFP-CN11b and pTRE-Tight-YFP-CD18 were constructed by recombinant DNA technique. The 2 vectors were co-transfected into CHO cells using liposome to fuse CD11b and CD18: the 2 subunits of Mac-1. Fluorescence microscope was used to observe the cyan fluorescence and the yellow fluorescence of Mac-1-FP.
