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The adverse drug interactions can be avoided by knowing the enzymology basis of drug metabolism,common substrates,inductors,inhibitors involved and using the same kind of drugs rationally. 认识药物代谢的酶学基础,了解药酶的常见底物、诱导剂和抑制剂,合理选用同类药品,能避免有害药物代谢性相互作用的发生。
Keywords selective serotonin reuptake inhibitors;metabolism;drug interaction;prescription analysis;adverse drug reaction; 羟色胺再摄取抑制剂;代谢;药物相互作用;用药分析;药物不良反应;
Adverse drug interaction 不良相互作用
This paper reviews the rational use of fluoroquinolones from the feature of antibiosis,drug resistance,indication,adverse effect,drug interaction,and so on. 从抗菌特点、耐药性、适应证、不良反应、药物相互作用等方面综述了氟喹诺酮类抗菌药物的合理应用。
This drug can also interact with other medications that patients may be taking and increase their risk of adverse drug events. 这种药物还会与病人服用的其他药物相互作用,增加药物不良反应的风险。
Keywords antipsychotic agents;pharmacology;pharmacokinetics;drug interactions;ziprasidone;adverse drug reaction; 抗精神病药;药理学;药动学;药物相互作用;齐哌西酮;药物不良反应;
The rate of adverse drug reaction (ADR) in I group was 4.7%. [结果 ] 组有 194例为显效 ;显效率 82 .;6%25;不良反应发生率为 4
However, Some of them also have adverse reaction, especially cardiotoxicity, which is related to antihistamines drugs interaction, pharmacokinetics and drug molecular structure. 但第2代抗组胺药仍有一些不良反应,尤以心脏的毒性作用,这与抗组胺药物相互作用、药动学、以及药物的分子结构有关。
METHODS 124 cases reports of Adverse Drug Reaction (ADR) were analyzed. 方法对124例药品不良反应(ADR)报告进行分析。
Neurotoxicity is the most common adverse drug reaction seen in clinic. 神经系统毒性反应是药物常见的毒性反应。
The results suggested that there is drug interaction between RFP and CRL, and no interaction between CRL and CMT. 结果表明:RFP与CRL存在着药物相互作用,而CMT与CRL相互作用不明显。
The literature on the Ciprofloxacin-induced adverse drug reactions (ADR) was reviewed in this article. 目的：综述环丙沙星引起的各种不良反应的文献报道。
This study analyzes the methods, efficacy and adverse drug reactions (ADR) of domestic literatures on venlafaxine. 本文对该药的使用方法、临床疗效、不良反应等进行汇总分析。
The method of Chou and Talalay was utilized to assess the type of drug interaction, i.e. 50% inhibited concentration (IC50) and combined index (CI). 利用Chou 和 Talalay法计算两药的中效浓度（IC50）及合用指数CI。
Lindahl K, Schvarcz, R.; Bruchfeld A.et al. Clinical pharmacology. Adverse drug interactions. BMJ 1981;282(6260):288-91. 行政院卫生署药品交互作用资料库教育训练讲义;2006.
The analgesic effects and adverse drug reactions(ADR)after analgia 4h,8h,12h and 24h were observed and recorded. 分别于镇痛开始后4小时、8小时、12小时、24小时观察并记录镇痛效果及不良反应。
URSA is more objective than Loewe Additivity model in reflecting the degree of drug interaction, moreover, URSA can describe the relation between dose and effect. URSA比LoeweAdditivity模型能更客观的反映药物相互作用的程度,且URSA可描述联合药物的量效关系。
Fluvoxamine treatment arising in the course of adverse drug reactions than clomipramine light. 氟伏沙明治疗过程中出现药物不良反应较氯米帕明轻。
Nurse should enhance learning knowledge of clinical pharmacy,including generic names and new forms of durgs,drug interaction,infusion compatiblity,chronopharmacology,etc. 提出护士应加强心血管药物通用名、新剂型、输液配伍化学、时辰药理学知识的学习。
OBJECTIVE:To analyze the related factors that initiating the occurrence of adverse drug reactions (ADR). 目的 :了解我院药品不良反应 (ADR )发生及引发的相关因素。