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- HE and Masson Trichrome staining, quantitative measurement of tubulointerstitial fibrosis degree were carried out. 梗阻肾组织用HE和Masson染色后,光镜观察其病理变化并进行图像分析评定各组肾小管间质损害及纤维化程度;
- Emerging evidence suggests that tubular epithelial-mesenchymal transition (EMT) is an important factor in renal tubulointerstitial fibrosis. 摘要肾小管上皮细胞转分化在肾间质纤维化发生中起到重要作用,其转化条件和机制已成为当今学者研究的热点。
- Tubulointerstitial fibrosis is the common consequence and pathological change of several kidney diseases in the progression to end-stage renal failure. 肾间质纤维化是多种肾脏疾病进展到终末期肾衰竭的共同途径和主要病理基础。
- Conclusion: Irbesartan can up-regulate the renal HGF, strengthen its renotrophic function and retard the development of glomerular sclerosis and tubulointerstitial fibrosis. 结论:厄贝沙坦可以上调肾组织HGF的分泌,加强HGF的肾保护作用,延缓肾小球硬化,减轻肾小管-间质纤维化。
- OBJECTIVE : The tubulointerstitial fibrosis(TIF) and progressive deterioration of the renal impairment are almost the common pathway by which all the kidney diseases progress to end stage renal failure. 目的:肾间质纤维化导致肾脏损害进行性发展,几乎是所有肾脏疾病进展至终末期肾功能衰竭的共同途径。
- Objective: Diabetic nephropathy (DN) encompasses a complex of structure alterations, including the hypertrophy of glomerulus and renal tubule in early stage, and glomerulosclerosis, tubulointerstitial fibrosis (TIF) in late stage. 目的:糖尿病肾病(diabetic nephropathy, DN)的病理变化复杂,早期主要表现为肾小球和肾小管的肥大,晚期则表现为肾小球硬化及肾小管间质纤维化。
- In the pathological sections of model group,focal segmental glomerular sclerosis,dropsy in renal tubular epithelial cells,protein cast in some renal tubules and tubulointerstitial fibrosis could be seen. 病理形态学观察:模型组肾小球呈局灶性节段性硬化,肾小管上皮细胞水肿,部分小管腔内可见蛋白管型,肾间质纤维化;
- renal tubulointerstitial fibrosis 肾间质纤维化
- Spironolactone ameliorates renal tubulointerstitial fibrosis of rat unilateral ureteral obstruction model 螺内酯抑制大鼠单侧输尿管梗阻后肾间质纤维化
- The mechanism study of Bailing capsules preventing tubulointerstitial fibrosis in the rats 百令胶囊防治大鼠肾小管间质纤维化的实验研究
- Retinoic acid suppresses tubulointerstitial fibrosis of rat unilateral ureteral obstruction model 维甲酸抑制大鼠单侧输尿管梗阻模型肾间质纤维化
- Keywords Cantharidin;Proteinuria;renal tubulointerstitial fibrosis;human proximal tubular epithelial cell; 关键词斑蝥素;蛋白尿;肾间质纤维化;人近端肾小管上皮细胞;
- Keywords Spironolactone;Unilateral ureteral obstruction;Renal tubulointerstitial fibrosis; 螺内酯;单侧输尿管梗阻;肾间质纤维化;
- Keywords Hirudo;tissue-type plasminogen activator;glomerulosclerosis;tubulointerstitial fibrosis; 关键词水蛭;纤溶酶原激活物;肾小球硬化;间质纤维化;
- Keywords 5/6 Nephrectomy remnant young rats;Fibrinolysis system;Extracellular matrix;Tubulointerstitial fibrosis; 6肾切除大鼠;纤溶系统;细胞外基质;肾间质纤维化;
- Preventive and therapeutic effects of spironolactone on renal tubulointerstitial fibrosis after unilateral ureteral obstruction in rats 螺内酯对梗阻性肾病大鼠肾间质纤维化的防治作用
- Change of vascular endothelial growth factor in renal tubulointerstitial fibrosis after unilateral ureteral obstruction in rats 血管内皮生长因子在梗阻性肾病大鼠肾间质纤维化中的变化
- Phenotypic changes of renal tubular epithelial cells and role of tubulointerstitial fibrosis in children with glomerular disease 小儿肾小球疾病的肾小管上皮细胞表型特征及其纤维化关系探讨
- Experimental Study on Effect of Matrine in Alleviating Renal Tubulointerstitial Fibrosis in Unilateral Ureteral Obstruction Model 苦参碱对单侧输尿管梗阻模型大鼠肾小管间质纤维化的影响
- Keywords myo-inositol oxygenase;diabetic nephropathy;rats;tubulointerstitial fibrosis;renal tubular epithelial cells;expression; 糖尿病肾病;肾小管间质纤维化;肌肌醇加氧酶;大鼠;肾小管上皮细胞;表达;