p27Kip1 is a cdk inhibitor that regulates cell cycle progression from the Gl phase to the S phase by binding to the cyclin E/ cdk2 complex, there by inhibiting this kinase.

• p27~(Kip1)是一个cdk抑制物，通过结合在CyclinE/cdk2复合体上，调控细胞周期中G1期到S期进展，从而抑制此激酶。