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- muscarinic receptor modulation 蕈毒碱受体调节
- The modulatory effect of Ach on the IATP may be achieved by activating muscarinic receptor (M receptor). 乙酰胆碱对I(下标ATP)的调制作用是通过毒蕈碱样乙酰胆碱受体(M受体)激活实现的。
- M5 muscarinic receptor may be a useful pharmacological target for the treatment of heroin addiction. M5毒蕈碱受体可作为改变海洛因行为学效应的有效药理学靶点之一.
- Pirenzenpine is a relatively selective M1 subtype muscarinic receptor antagonist and used to treat digestive system ulcer. 哌仑西平是一种M1受体选择性的抗胆碱药,临床上用于治疗消化性溃疡。
- At the end of observation, the activity of AChE and ATPase and the gene expression of muscarinic receptor, M1 and M2 in cardiac muscle were measured. 同时测定心脏AChE活力、ATPase活力和M1、M2受体基因表达水平。
- Nilvebrant L, Hallen B, Larsson G.Tolterodine, a new bladder selective muscarinic receptor antagonist: Preclinical pharmacological and clinical data[J].Life Sci,1997,60:1129. 吴士良;杨勇;薛兆英;等.;新型抗胆碱能药物托特罗定治疗膀胱过度活动症的临床研究[J]
- In contrast, microinjection of M5 muscarinic receptor sense oligonucleotide (S-ONs) into the VTA did not block the expression of behavioral sensitization or the expression of FosB in the NAc or DG in the heroin sensitized rats. 但VTA中注射有义寡核苷酸(M5S-ONs)不能明显抑制大鼠行为敏化的表达,也不能抑制海洛因敏化大鼠NAc和DG中FosB蛋白的表达。
- The enhancement of FosB-positive neurons in the NAc or DG could be inhibited by microinjection of M5 muscarinic receptor AS-ONs into the VTA before the heroin-induced locomotor sensitization was performed. 海洛因诱导的行为敏化大鼠中NAc及DG中的FosB免疫反应阳性神经元的表达增加,而在VTA内注射M5AS-ONs能明显抑制NAc及DG中FosB阳性神经元表达的增加;
- Oligosaccharides, especially the glycans of the glycoconjugates, play important roles in the cell recognition, signal transduction and receptor modulation phenomena in the life processes. 寡糖,尤其是糖缀合物中的寡糖链,在生命过程的细胞识别、信号传导和受体调节现象中扮演着重要的角色。
- The key is something called a selective androgen receptor modulator, or SARM. 关键是所谓选择性雄激素受体调节剂,或行动情报处。
- Specific binding is found in tissues where muscarinic receptors are demonstrable pharmacologically. 在药理学方法证明有毒蕈碱样受体的组织中发现了特异的结合作用。
- acetylcholine m2 muscarinic receptor 毒[曹十]碱乙酰胆碱m2受体
- AIM To examine whether the endo-thelial-target for acetylcholine is different from muscarinic receptors. 目的研究内皮细胞乙酰胆碱靶标与M受体药理学特征的差异。
- Objective To synthesize raloxifene hydrochloride, which is a selective estrogen receptor modulator. 目的合成选择性雌激素受体调节剂盐酸雷洛昔芬。
- non-neuronal muscarinic receptor 非神经性M受体
- anti- M2 muscarinic receptor autoantibody M2受体自身抗体
- To develop a new selective steroid receptor modulator is one of the targets in future study to treat osteoporosis. 开发选择性类固醇激素受体调节剂有望成为未来防治骨质疏松药物的研究方向。
- Aim To clone the muscarinic receptors M1, M3 and M5 sequences of astrocyte cells,and compare the gene and protein sequences with those of neurons. 目的克隆胶质细胞M1、M3、M5受体亚型基因序列,比较胶质细胞和神经细胞M1、M3、M5受体亚型基因序列、蛋白质序列的差异。
- We proved the existence of muscarinic receptors and vagal nerves innervation in ventricle with histochemical staining and molecular biological methods. 通过组织化学染色及分子生物学方法进一步证明心室有毒蕈碱受体分布;
- Clomiphene (estrogen receptor modulator) and some natural or synthetical progestogens can help to control the seizure of some epilepsy patients. 雌激素受体调节剂-克罗米酚以及天然或者合成的孕激素对一些癫痫患者的发作有效。