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- QT-SLN was spherelike and smooth/The mean diameter was 2173nm and the entrapment efficiency was 48.50%. 槲皮素固体膳质纳米粒为圆整的类球形实体粒子;平均粒径为2173nm;包封率为48.;50%25。
- The entrapment efficiency in cationic liposomes was in the same range even if the drug loading was increased. 即使填充药量增加,带有阳离子的脂质体的包封率(仍处于相同范围)没有变化。
- To prepare clindamycin phosphate liposome, and to determine the entrapment efficiency and particle diameter of it. 目的制备克林霉素磷酸酯脂质体并测定包封率及粒径。
- AIM:To establish a method of determining the entrapment efficiency of bulleyaconitine A multivesicular liposomes. 目的:建立测定草乌甲素多囊脂质体包封率的方法。
- OBJECTIVE To evaluate the quality of astragaloside liposome and determine its entrapment efficiency. 目的对黄芪皂苷脂质体进行质量评价,测定黄芪皂苷脂质体的包封率。
- The volume ratio of oil and water(W_1/O) had the most evident effect on entrapment efficiency among thr... 第一水相的体积对微球的表面形态影响很大,第一水相的比例越大,会在微球的表面留下更多的孔隙结构。
- Objective: To establish an HPLC method for the determination of entrapment efficiency of sinomenine liposomes. 目的:建立青藤碱脂质体包封率的测定方法。
- Aim To prepare integerrimine (INT ) liposomes with high drug entrapment efficiency ( DEE ) and good stability and then make them into liposomal gel. 目的制备具有高包封率和良好稳定性的全缘千里光碱(INT)脂质体,并将其制成凝胶剂。
- There are slight differences of content ,the entrapment efficiency and accelerated test between liposome and proliposome. 冻干前后脂质体的含量和包封率变化不大,离心加速试验的结果也没有明显区别。
- The sustained release microsphere has relatively higher entrapment efficiency, drug-loading rate as well as remarkable sustained release function. 该缓释微球具有较好的包封率和载药量,以及明显的缓释作用。
- The mean diameter of the prepared AmB-PBCA-NP was 94.38 nm; the mean entrapment efficiency of the particles was 82%; and the drug loading rate was 56.10%. AmB-PBCA-NP平均粒径94.;38 nm;平均包封率为82%25;载药量56
- METHODS:Alprostadil liposome was prepared by instillation technique,and technical conditions were optimized with particle size and entrapment efficiency as indexes. 目的:对制备前列地尔脂质体的工艺条件进行优化。
- Methods ATRA liposomes was prepared by reverse evaporating method and to determine the concentration and the entrapment efficiency of ATRA liposomes by HPLC. 方法采用逆相蒸发法制备全反式维甲酸脂质体,高效液相色谱法检测活性药物含量及包封率,并进行加速试验检测其初步稳定性。
- HPLC method was established for the determination of the entrapment efficiency of the liposomes loaded with vincristine sulfate and mitoxantrone hydrochloride. 建立了HPLC法测定硫酸长春新碱和盐酸米托蒽醌复方脂质体的包封率。
- Aim:To prepare wogonin liposomes with high entrapment efficiency(EE) and desirable size,and to study in vitro release of the liposomes and its pharmacokinetics in rats. 目的:制备包封率高且粒径适宜的汉黄芩素脂质体,考察其体外释放及大鼠体内药代动力学。
- And the drug entrapment efficiencies of different drug/albumin ratios were higher than ... 制得的微球载药量高,具有明显缓释作用。
- Conclusions Using film-sonication method can prepare liposome with high entrapment efficiency and uniform size distribution.There are no obvious difference between liposome and proliposome. 结论 采用薄膜分散-超声法能够制备出包封率较高、粒径比较均匀的脂质体,经冷冻干燥后,其各项性质没有明显的变化。
- ABSTRACT Objective To prepare capreomycin sulfate liposomes to develop a method for determining its drug content and entrapment efficiency and to study the release profile in vitro. 目的制备硫酸卷曲霉素脂质体,建立含量和包封率的测定方法,初步考察其体外释放规律。
- The mean entrapment efficiencies determined by minicolumn centrifugation method or ultracentrifugation method were 94.3% and 97.9% respectively. 用微柱离心法和冷冻超速离心法测得该脂质体的平均包封率分别为94.;3%25和97
- Methods To prepare matrine liposomes by passive loading method and avtive loading method,the entrapment efficiencies were determined by minicolumn centrifuge-UV method. 方法采用被动载药和主动载药制备脂质体,用微柱离心-紫外分光光度法测定脂质体包封率。