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Keywords cervical cancer;human papillomavirus;circulating tumor DNA;tumor marker; 宫颈癌;人类乳头状瘤病毒;循环肿瘤DNA;肿瘤标志物;
circulating tumor DNA 循环肿瘤DNA
The combinational detection of circulating DNA and telomerase of circulating tumor cells is useful for the early diagnosis of tumors. 循环DNA和肿瘤细胞端粒酶的联合检测,对于肿瘤早期诊断有重要意义。
If the tumor DNA to be sequenced is too heterogeneous, some important mutations may be missed. 如果定序出来的肿瘤细胞DNA异质性过高，其中某些重要突变将遭到忽视。
The concept of existence of circulating tumor cells(CTCs)has a history of over 100 years. 有关循环肿瘤细胞的理论已有很长时间。
The metastasis and recurrence progress of the solid tumor are highly associated with the circulating tumor cell invade cascade. 肿瘤转移及复发的过程均是一个循环肿瘤细胞定植生长的级连放大的瀑布反应。
Based on the CTC theory,detecting circulating tumor cell would help the clinician finding early metastasis or recurrence more effectively. 基于肿瘤细胞播散理论,检测循环肿瘤细胞可更早期有效发现肿瘤的早期转移和复发。
Conclusions Disruptive TP53 mutations in tumor DNA are associated with reduced survival after surgical treatment of squamous-cell carcinoma of the head and neck. 结论肿瘤DNA破坏性TP53基因突变与手术后头颈部鳞状细胞癌生存率下降有关。
We detected the T790M mutation, which confers drug resistance, in circulating tumor cells collected from patients with EGFR mutations who had received tyrosine kinase inhibitors. 在从接受酪氨酸激酶抑制剂治疗患者中收集的循环肿瘤细胞中，我们检测到了引起耐药的T790M突变，
The CTC-chip was able to reproducibly isolate circulating tumor cells in quantities that were large enough to allow molecular analyses, the authors concluded. 作者结论表示，CTC-晶片可以再现分离量化循环肿瘤细胞，而足以进行分子分析。
The study showed that the CTC-chip could reproducibly isolate circulating tumor cells in quantities that were sufficient and pure enough to allow for molecular analysis. 研究显示，CTC-晶片可以再现分离量化循环肿瘤细胞，足以适当进行分子分析；
Of the 12 patients with specimens from the primary tumor, circulating tumor cells, and plasma, genotyping of circulating cells had a sensitivity of 92%;the sensitivity for plasma genotyping was 33%. 12名原发肿瘤病患的样本中，循环肿瘤细胞、血浆与循环细胞基因型的敏感度都是92%25，血浆基因型的敏感度为33%25。
He gave away his books to a circulating library. 他把自己的书籍损赠给一家循环图书馆。
Rumours are circulating in Whitehall. 怀特霍尔街上流传著谣言。
Keywords liposomes RNA interference ovarian neoplasms carcinoma cisplatin cell line;tumor DNA repair gene expression; 脂质体;RNA干扰;卵巢肿瘤;癌;顺铂;细胞系;肿瘤;DNA修复;基因表达;
A malignant tumor originating in glandular tissue. 腺癌起源于腺性组织的恶性肿瘤
The surgeon operated on her for a tumor. 医生为她的肿瘤开刀。
The surgeon operated on him to remove the tumor. 外科医生给他做手术以切除肿瘤。
A surgeon removed the boy's brain tumor. 一位外科医生为这男孩摘除了脑肿瘤。
DNA fingerprinting can help the police to find the criminals. DNA指纹术有助於警察发现罪犯。