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- Objective To introduce a rapid method of isolateing and culturing cardiac myocyte of neonatal rats and to compare the difference with cardiac fibroblast. 目的 探索一种快速分离和培养新生大鼠心肌细胞的方法，比较心肌细胞和成纤维细胞的形态差异。
- AcSDKP can inhibit proliferation and collagen synthesis in cultured rat cardiac fibroblasts mediated by PDGF. AcSDKP对PDGF介导的心脏成纤维增殖和胶原合成均有明显抑制作用,这可能与其抗心脏纤维化的作用相关。
- AcSDKP further increased MMP-2 and MMP-9 activity and MMP-1 expression of cardiac fibroblasts induced by 10% FBS and PDGF. AcSDKP能够进一步增加由10%25血清和PDGF诱导的心成纤维细胞MMP-2、MMP-9的活性,并促进MMP-1的表达。
- Objective: To investigate the effects of lysophosphatidic acid (LPA) on the proliferation and collagen synthesis of cardiac fibroblasts(CFs) in vitro culture. 目的观察溶血磷脂酸(LPA)对体外培养心脏成纤维细胞(CFs)的增殖与胶原合成的影响。
- Objective To investigate the effects of tetramethylpyrazine (TMP) on the proliferation and collagen synthesis of cardiac fibroblasts (CF) in vitro culture. 目的观察川芎嗪(TMP)对体外培养心脏成纤维细胞(CF)的增殖与胶原合成的影响。
- Myocardium collagen metabolic regulation involves intersitital cells major cardiac fibroblasts, myofibroblasts, smooth muscle cells, endothelial cells, and pericytes. 涉及心肌胶原代谢调控的间质细胞主要有成纤维细胞、肌成纤维细胞、平滑肌细胞、内皮细胞、周细胞等。
- Results: On the culture of 0.4% FBS,PDGF stimulated cardiac fibroblasts proliferation and collagen synthesis with a dose-dependent manner at the concentrations from 1 ng/ml to 20 ng/ml,in which 10 ng/ml PDGF reached its peak. 采用3H-脯氨酸掺入法检测心脏成纤维细胞胶原的合成。 结果:PDGF在1~20 ng/ml浓度范围内对心脏成纤维细胞增殖和胶原合成均有促进作用。
- AIM: To investigate the effects of matrine on the proliferation and collagen synthesis of rat cardiac fibroblasts(CFs) induced by aldosterone(Ald),to research the mechanism of regression of heart fibrosis. 目的：研究苦参碱(Matrine，Mat)对醛固酮(aldosterone，Ald)诱导新生大鼠心肌成纤维细胞(Cardiac Fibroblasts，CFs)增殖及胶原代谢的影响，探讨其抑制心肌纤维化的机制。
- Methods Cardiomyocytes and cardiac fibroblasts were isolated by trypsin digestion method. DNA and protein synthesis were measured by 3 H-deoxythy-midine( 3 H-TdR) and 3 H-Leucine( 3 H-Leu) incorporation. Protein content was measured by Bradford method. 方法采用体外乳鼠心肌细胞和心脏成纤维细胞培养,一定浓度的ET-1、ANP单独或联合作用细胞24h,以3H-胸腺嘧啶脱氧核苷(3H-TdR)、3H-亮氨酸(3H-Leu)掺入法测定细胞DNA、蛋白合成,Brad-ford法测细胞总蛋白含量,RT-PCR法测心肌细胞心钠素ANPmRNA的表达,评价ET-1、ANP对心肌细胞和成纤维细胞的作用。
- Laser scanning confocal microscopy on vimentin and mitochondrion in cardiac fibroblast of rat 乳鼠心成纤维细胞波形蛋白和线粒体表达的激光扫描共聚焦显微镜观察
- Keywords tetramethylpyrazine;cardiac fibroblast;proliferation;collagen synthesis; 川芎嗪;心脏成纤维细胞;增殖;胶原合成;
- One example of this kind of cell is the fibroblast. 例如成纤维细胞就属于这种细胞。
- Human Fibroblast surface protein，FSP Elisa K... 人纤维母细胞表面抗原（FSP）试剂盒；
- A patient whose heart has stopped beating, as in cardiac arrest. 心脏已停止跳动的病人心脏已停止跳动的病人，如患心脏病
- cardiac fibroblast 成心肌(纤维)细胞
- cardiac fibroblast cells 心脏成纤维细胞
- Epinephrine is a powerful cardiac stimulant. 肾上腺素是一种强效心脏兴奋药。
- Cardiac output was measured by thermo dilution. 用热稀释法测定心输出量。
- The third cardiac malposition is dextrocardia. 第三种心脏位置异常是右位心。
- Non-mitogenetic human acidic fibroblast growth factor, nm-haF-GF. 和人酸性成纤维细胞生长因。
