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alkylating agents mutagenesis 烷化剂诱变
The hydrocarbon diperchlorate products have utility as detonatable sensitizers for explosives and alkylating agents. 二过氯酸烃基酯产物可用作起爆药的敏化剂及作为烷化剂。
DNA repair pathways can enable tumor cells to survive DNA damage induced by anti-tumor drugs such as alkylating agents. DNA损伤修复能够使肿瘤细胞耐受化疗药物造成的DNA损伤而存活,因此,调节某种特殊的DNA修复路径可以增强化疗药物的疗效。
Etoposide or alkylating agents should get complete blood counts (CBCs) yearly for evidence of myelodysplasia or a secondary leukemia. 依托泊苷或者烷化剂的治疗应该每年接受全血细胞计数检查，以监测骨髓发育不良或继发性白血病的发生迹象。
Long alkyl groups were introduced to the upper rim of calix [4] arenes by Friedel-Crafts reaction of calix [4] arenes and long alkylating agents. 脱叔丁基的杯[4]芳烃与长链的叔醇或者叔氯代烷烃进行傅-克反应,在其上端引入长链烷基。
Abstract Long alkyl groups were introduced to the upper rim of calyx[4]arenes by Friedel-Crafts reaction of calyx[4]arenes and long alkylating agents. 摘要脱叔丁基的杯[4]芳烃与长链的叔醇或者叔氯代烷烃进行傅-克反应，在其上端引入长链烷基。
The synthetic process of 2,4di?tert?butylphenol was studied in a batch reactor, while isobutylene was used as alkylating agent. 以异丁烯为烷化剂 ,在间歇反应釜中研究了苯酚烷基化反应合成 2 ,4二叔丁基苯酚的反应工艺。
The three chemical mutagens were mitomycin C(MMC,DNA crosslinker),bleomycin(BLM,radiometric agent),methyl methanesulfonate(MMS,alkylating agent). 3种化学诱变剂是丝裂霉素C(MMC ,DNA交联剂 )、博来霉素 (BLM ,似X线剂 )、甲基甲烷磺酸酯 (MMS ,烷化剂 )。
Background : Bendamustine, a bifunctional alkylating agent with anticipated purin-like properties is active in metastatic breast cancer (MBC) patients. 苯达莫司汀，具有烷化剂和嘌呤类似的双相功能可以在转移性乳腺癌（MBC）患者中发挥作用。
We reported a case of multiple myeloma, who suffered from the acute myelomonocytic leukemia (AML-M4) after the chemotherapy of alkylating agent. 摘要报道1例我院收治的多发性骨髓瘤患者治疗后继发急性髓系白血病（M4型）。
Conclusions QJYS noticeably inhibits the teratogenesis of CP,reduces the DNA injury caused by this alkylating agent,and improves its tumoricidal effect. 结论QJYS可显著降低CP的致畸毒性，减轻烷化剂对DNA的损伤，改善CP的抑瘤效果。
Pediatric patients with low-risk Hodgkin's disease can be cured with therapy without an alkylating agent, bleomycin, etoposide, or high-dose, extended-field radiotherapy. 儿童低危型霍奇金氏病不必使用烷化剂、博莱霉素、鬼臼乙叉甙或大剂量扩野放疗等也可治愈。
It is currently approved to treat B cell chronic lymphocytic leukemia (CLL) in patients who have been treated with alkylating agents and who have not responded to fludarabine therapy. 当前它被批准用于那些曾使用过烷基化试剂治疗和那些对氟达拉滨治疗反应无效的B细胞性慢性淋巴细胞白血病患者的治疗。
O6-Methylguanine-DNA methyltransferase(MGMT)is an important DNA repair gene in human cells.It plays an important role in resisting cellular DNA damage induced by alkylating agents. O6甲基鸟嘌呤DNA甲基转移酶(MGMT)是细胞中一种重要的DNA损伤修复酶,它在抵御烷化剂所致的细胞突变和死亡中起重要作用。
The continuous synthetic process of 2,4 di tert butylphenol was studied in a tubular fluid bed reactor, while isobutylene was used as alkylating agent and strong acidity positive ion exchange resin as catalyst. 以强酸性阳离子交换树脂为催化剂 ,异丁烯为烷基化剂 ,在管式流化床连续反应器中研究了苯酚烷基化反应合成 2 ,4 二叔丁基苯酚的反应工艺。
The effects of reaction medium, PTC, amounts of NaOH and alkylating agent cetyl bromide as well as reaction time and temperature on thedegree of substitution of N-cetylchitosan werestudied. 研究了反应介质、催化剂种类、碱的用量、烷化剂用量、反应时间、反应温度等因素对壳聚糖衍生反应的影响。
Polystyrene - supported N - benzyl - N - alkyl - aminopyridine was prepared through chloromethylated polystyrene treated with 4 - aminopyridine and alkylation agents. 本文以聚苯乙烯氯球为原料，通过与4-氨基吡啶及烷基化试剂反应，制成聚苯乙烯支载N-烷基-N-苄基氨基吡啶催化剂。
According to the process a side-chain of a substituted aromatic compound is alkylated by reacting the aromatic compound with an alkylating agent in the presence of a catalyst. 根据该方法，在催化剂的存在下，通过使芳香化合物与烷基化剂反应，使取代的芳香化合物的侧链被烷基化。
The alkylation reaction of chlorinated polypropylene (CPP) as alkylating agent with toluene catalyzed by aluminum chloride (AlCl3) has been investigated in detail. 研究了氯化聚丙烯与甲苯在三氯化铝(AlCl3)催化下的烷基化反应。
Double agents live in a perpetual state of fear. 两面派永远过着提心吊胆的生活。