Wright and McCumbee has reported that the erythrocytes of spontaneously hypertensive rat (SHR) contains a hypertensive factor (HF) and a antihypertensive factor (AHF).

• 抗高血压因子(antihypertensive factor，AHF)是1985年Wright实验室在研究自发性高血压大鼠(SHR)红细胞膜中存在的高血压因子(hypertensive factor，HF)时发现的。