Women with BRCA1 mutations are at very high risk for breast cancer at an early age. Those who know they carry the mutation sometimes choose preventive mastectomies.

• 带有BRCA1突变的妇女在早期患乳腺癌具有很高的机率。那些知道自己带有这种突变基因的妇女有时会选择预防性的乳房切除。