With the clinical situation and experimental result, CRFR1 can therapia IBS, and supply the evidence of inflammatory bowel disease.

• 根据临床表现和实验结果提示，CRFR1受体拮抗剂可能对类似IBS的功能性肠病有治疗意义，并且也为使用CRFR1拮抗剂治疗炎症性肠病提供了依据。