When the pH of the reaction medium is 7,the substitute reaction time is 8 h,the time of acid cleavage is 2 h and the amount of Zn is 0.77 mol/mol(3-chloropropionic acid),the yield of 3-mercaptopropionic acid is 78% and the minimum purity is 99%(GC).

• 当控制取代反应介质pH=7；酸解反应时间2 h；锌粉和3-氯丙酸摩尔比为0.；77时；3-巯基丙酸收率高达78%25；纯度大于99%25(GC)。