When bound to calcium ions, calmodulin changes shape and phosphatases, that are involved in signaling pathways, activating or inactivating them.

• 钙调蛋白本身没有活性，当和钙离子结合后，会引起钙调蛋白构象的改变，使之与其他蛋白酶如激酶或磷酸酶结合，调节细胞信号传导。