When assisted with D(+)gluconie acid d-lactone and with low COBE concentration (0.1g/100mL), 106 yeast can reduce COBE to CHBE with an enantiomer excess of more than 98%.

• 106 酵母以葡聚糖内酯为辅底物时；在较低的底物浓度0.；1g/100mL 时；R-构型产物的光学纯度可达98%25以上。