We reported the first case of stiff skin syndrome in China,which had typical clinical manifestation and histological features.Staining of Alcian blue in biopsy was positive.

• 我们首次诊治1例幼儿皮肤僵硬综合症患者，具有典型的临床表现和组织病理，阿新兰染色阳性，给以丹参等治疗，症状缓解。