We proposed that the migration and mixing are the dominant driving force of the HLA gene flow while the genetic drift caused by isolation and the nature selection have an important influence on HLA genetic structure.

• 认为群体迁移、融合而产生的基因流动是HLA基因频率变化的主要动力，但隔离导致的遗传漂变以及自然选择也有重要影响。