We got a better result by the improvement of synthesis of 4-hydroxycoumarin and sodium warfarin, the purity was more than 98%, the yield was more than 90%.

• 本文还对4-羟基香豆素以及华法林钠的合成工艺进行了改进,获得了较好的结果,经HPLC分析含量都在98%25以上,收率都在90%25以上。