VES had no effects on p38 and ATF-2. Antisense to ATF-2 oligomers also had no effect on VES-mediated apoptotic rate.

• VES 并不改变p38 蛋白的表达,且其下游转录因子ATF-2 的表达未发生改变,转染ATF-2反义寡聚核苷酸后VES 诱导的细胞凋亡亦未发生改变。