Using labe1led streptavidin - biotin (LSAB) methed, we exandned the expression of cyclin- dependent kinases 4 inhibitor P 16 (CDK4I ) in 83 cases of human non-sman cull lung cancer,the average rate of P16 protein positive expression was 65. 93%.

• 为研究CDK4I/P16与非小细胞肺癌的发生及发展的关系，应用免疫组化LSAB法研究了83例肺癌手术标本中CDK4I蛋白的表达。 结果显示，CDK4I蛋白表达平均阳性率为65.；93%25。