Using avidin-biotin complex method (ABC), we demonstrated that BMP mainly existedin the tumor cell plasma and some tumor-like bone tissues with positive staining in-12 out of 14 osteosarcoma patients and in all the four cases of chonbrosarcoma.

• ABC法染色阳性12/14(骨肉瘤); 4/4(软骨肉瘤)结果显示,BMP主要分布于骨和软骨肉瘤的肿瘤细胞胞浆及部分肿瘤性骨组织中,从而证实骨、软骨肉瘤都含有丰富的BMP。