Using L-proline as raw material, (2R,3R)-tartaric acid as resolution agent, D-proline was prepared by asymmetric transformation, i.e. the D-proline was reacted with acetyl chloride, triethylamine and (BOC)_2O one after another.

• 以L脯氨酸为原料、(2R,3R)酒石酸为拆分剂,采用不对称转换的方法将L-脯氨酸转换成D-脯氨酸。