Under isotonic conditions, no single channel activities were observed in most patches. Hypotonic superfusion-induced cell swelling resulted in the appearance of active channel.

• 等渗状态下；用细胞贴附式记录；多数心肌细胞膜片无通道活动；用低渗溶液灌流细胞；在细胞容积增大的同时；出现单通道电流的激活.