Topical anesthetic is well known for its toxicity to the cornea by causing punctate epithelial keratopathy, chronic epithelial defect with rolled edge, and even stromal infiltration.

• 摘要局部麻醉剂所造成的角膜病变容易被忽略且不易诊断；其表现包括点状角膜上皮病变，边缘捲起的慢性上皮缺损，严重者甚至会形成环状角膜基质浸润。