To diagnose APS, at least one of two clinical criteria (vascular thrombosis and complications of pregnancy) and at least one of two laboratory criteria (lupus antibody and anticardiolipin antibody) must be met.

• 灾难性抗磷脂症候群是抗磷脂症候群中罕见的急症，大多有特别的诱发因子，最常见为感染或手术。