To address this question, we investigated the effect of a2-adrenoceptor stimulation on field excitatory postsynaptic potential (fEPSP) and LTP by in vivo extracellular recording in area CA1.

• 本实验利用在体（in vivo）场电位记录技术，在海马CA1区局部注射a2受体激动剂clonidine或guanfacine，观察其对兴奋性突触后电位（field excitatory postsynaptic potential，fEPSP）和LTP的影响。