Through identification by HPLC,the result showed that Aspergillus niger produces CoQ10.The optimum saponification extracting conditions of coenzyme Q10 from Aspergillus niger with ultrasonic were studied by the orthogonal test design.

• 通过高效液相色谱鉴定证实黑曲霉菌体中含有辅酶Q10。 采用正交实验设计法,研究了超声辅助皂化提取黑曲霉中辅酶Q10的最佳工艺条件。